chloroethylnitrosocarbamoyl-alanyl-alanine

Base Information

• Chemical Name: chloroethylnitrosocarbamoyl-alanyl-alanine
• CAS No.: 93299-11-7
• Molecular Formula: C₉H₁₅ClN₄O₅
• Molecular Weight: 294.695
• Mol file: 93299-11-7.mol

Synonyms:chloroethylnitrosocarbamoyl-alanyl-alanine

Chemical Property of chloroethylnitrosocarbamoyl-alanyl-alanine

Chemical Property:

• Melting Point: 95 °C (hexane)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 128.17000
• Density: 1.49g/cm³
• LogP: 0.67780

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of chloroethylnitrosocarbamoyl-alanyl-alanine

There total 2 articles about chloroethylnitrosocarbamoyl-alanyl-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

L-alanin (56-41-7,25191-17-7,18875-37-1) + 1-(CNC-L-Alanyloxy)pyrrolidine-2,5-dione (125631-81-4) → CNC-L-Alanyl-L-alanine (93299-11-7)

Guidance literature:

With sodium hydrogencarbonate; In water; acetonitrile; for 0.666667h; Ambient temperature;

DOI:10.1002/ardp.19893221206

Reference yield:

N--L-alanine (80687-07-6) → CNC-L-Alanyl-L-alanine (93299-11-7)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC / tetrahydrofuran; CH₂Cl₂ / 1 h

2: 88 percent / NaHCO₃ / acetonitrile; H₂O / 0.67 h / Ambient temperature

With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water; acetonitrile;

DOI:10.1002/ardp.19893221206

upstream raw materials:

L-alanin

1-(CNC-L-Alanyloxy)pyrrolidine-2,5-dione

N--L-alanine

Refernces