1-Chloro-2-fluoroethane

Base Information

• Chemical Name: 1-Chloro-2-fluoroethane
• CAS No.: 762-50-5
• Molecular Formula: C2H4 Cl F
• Molecular Weight: 82.5052
• UNII: H83988O0RW
• DSSTox Substance ID: DTXSID1073234
• Nikkaji Number: J42.992I
• Wikidata: Q27279745
• Mol file: 762-50-5.mol

Synonyms:1-Chloro-2-fluoroethane;762-50-5;Ethane, 1-Chloro-2-fluoro-;TL 936;HCFC-151;HSDB 6787;Ethane,1-chloro-2-fluoro- (6CI,7CI,8CI,9CI);BRN 1730860;UNII-H83988O0RW;H83988O0RW;C2H4ClF;1-fluoro-2-chloroethane;2-chloro-1-fluoroethane;1-chloranyl-2-fluoranyl-ethane;DTXSID1073234;VEZJSKSPVQQGIS-UHFFFAOYSA-;MFCD00069127;AKOS006229034;1-CHLORO-2-FLUOROETHANE [HSDB];LS-65244;FT-0607598;A838656;Q27279745

Chemical Property of 1-Chloro-2-fluoroethane

Chemical Property:

• Vapor Pressure: 394mmHg at 25°C
• Melting Point: -76°C
• Refractive Index: 1.371
• Boiling Point: 53°C
• PSA: 0.00000
• Density: 1,168 g/cm3
• LogP: 1.19470
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 81.9985560
• Heavy Atom Count: 4
• Complexity: 10

Purity/Quality:

98%Min ^*data from raw suppliers

1-Chloro-2-fluoroethane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F,T
• Statements: 10-23/24/25-59
• Safety Statements: 16-36/37/39-45-59

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: C(CCl)F

Technology Process of 1-Chloro-2-fluoroethane

There total 4 articles about 1-Chloro-2-fluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydrogen fluoride (7664-39-3,12381-92-9,32057-09-3,74835-82-8) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → 1-chloro-2-fluoroethane (762-50-5) + 1-fluoroethylene (75-02-5,24981-14-4) + chloroethylene (75-01-4,9002-86-2)

Guidance literature:

at 300 - 400 ℃;

Reference yield:

2-chloroethyl benzenesulfonate (16670-48-7) → 1-chloro-2-fluoroethane (762-50-5) + 1,2-dichloro-ethane (107-06-2,52399-93-6)

Guidance literature:

With potassium fluoride; at 190 ℃;

Reference yield:

ethanol (64-17-5) → 1-chloro-2-fluoroethane (762-50-5) + 1,2-dichloro-ethane (107-06-2,52399-93-6)

Guidance literature:

With sulfur tetrafluoride; hydrogen fluoride; chlorine; at 125 ℃; for 4h; Rate constant; other temperature, reaction time, reagents ratio;

upstream raw materials:

2-chloroethyl benzenesulfonate

carbonofluoridic acid 2-chloro-ethyl ester

ethanol

hydrogen fluoride

Downstream raw materials:

2-phenoxy-1-fluoroethane

N,N'-diphenylethylenediamine

2-(2-fluoroethyl)isoindoline-1,3-dione

methyl 4-amino-3-(2-fluoroethoxy)benzoate

Refernces