1,3-Bis(4-piperidyl)propane

Base Information

• Chemical Name: 1,3-Bis(4-piperidyl)propane
• CAS No.: 16898-52-5
• Molecular Formula: C13H26N2
• Molecular Weight: 210.363
• Hs Code.: 2933399090
• European Community (EC) Number: 240-941-6
• NSC Number: 96364
• UNII: EU53EC219I
• DSSTox Substance ID: DTXSID6044850
• Nikkaji Number: J43.019F
• Wikidata: Q27277371
• ChEMBL ID: CHEMBL10749
• Mol file: 16898-52-5.mol

Synonyms:di-mu-iodobis(ethylenediamine)diplatinum (II);di-PIP;1,3-bis(4-piperidinyl)propane

Chemical Property of 1,3-Bis(4-piperidyl)propane

Chemical Property:

• Vapor Pressure: 0.00306mmHg at 25°C
• Melting Point: 65-68.5 °C(lit.)
• Refractive Index: 1.491
• Boiling Point: 278.5 °C at 760 mmHg
• PKA: 10.99±0.10(Predicted)
• Flash Point: 132.1 °C
• PSA: 24.06000
• Density: 0.894 g/cm³
• LogP: 2.81350
• Sensitive.: Hygroscopic
• Water Solubility.: almost transparency
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 210.209598838
• Heavy Atom Count: 15
• Complexity: 140

Purity/Quality:

99.9% ^*data from raw suppliers

1,3-Di-4-piperidylpropane >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CNCCC1CCCC2CCNCC2
• Uses: 4,4′-Trimethylenedipiperidine was used in the synthesis of hyperbranched copolymers from commercially available monomers: divinylsulfone, 4,4′-trimethylenedipiperidine and N-ethylenediamine. It was used in the synthesis of two- and three-dimensional cadmium-organic frameworks.

Technology Process of 1,3-Bis(4-piperidyl)propane

There total 6 articles about 1,3-Bis(4-piperidyl)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-di(4-pyridyl)propane (17252-51-6) → 1,3-di(piperidin-4-yl)propane (16898-52-5)

Guidance literature:

With hydrogenchloride; platinum; at 50 ℃; under 77228.3 Torr; Hydrogenation;

Reference yield:

4-vinylpyridine (100-43-6,329041-72-7) → 1,3-di(piperidin-4-yl)propane (16898-52-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium; hydroquinone; benzene

2: platinum; aqueous HCl / 50 °C / 77228.3 Torr / Hydrogenation

With hydrogenchloride; potassium; hydroquinone; platinum; benzene;

Reference yield:

picoline (108-89-4) → 1,3-di(piperidin-4-yl)propane (16898-52-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium; hydroquinone; benzene

2: platinum; aqueous HCl / 50 °C / 77228.3 Torr / Hydrogenation

With hydrogenchloride; potassium; hydroquinone; platinum; benzene;

upstream raw materials:

1,3-di(4-pyridyl)propane

((CH₃O)2C₆H₂(NO₂)CH₂OCOC₅H₉NCH₂)2CH₂

4-vinylpyridine

picoline

Downstream raw materials:

N,N-bis(4-cyanobenzyl)-4,4'-propylenebispiperidine

3,3'-(propane-1,3-diylbis(piperidine-4,1-diyl))dipropanenitrile

Refernces

• 1、 Arimitsu, Koji,Takemori, Yuri,Nakajima, Atsushi,Oguri, Ayaka,Furutani, Masahiro,Gunji, Takahiro,Abe, Yoshimoto. "Photobase generators derived from trans-o-coumaric acid for anionic UV curing systems without gas generation". . p. 1174 - 1177. Retrieved 2015/04/14.