2-(Biphenyl-4-yl)-5-phenyloxazole

Base Information

• Chemical Name: 2-(Biphenyl-4-yl)-5-phenyloxazole
• CAS No.: 852-37-9
• Molecular Formula: C21H15NO
• Molecular Weight: 297.356
• Hs Code.: 2934999090
• European Community (EC) Number: 212-711-5
• NSC Number: 87971
• UNII: S5HT3RX97E
• DSSTox Substance ID: DTXSID50234393
• Nikkaji Number: J195.125D
• Wikidata: Q83116164
• Mol file: 852-37-9.mol

Synonyms:852-37-9;2-(Biphenyl-4-yl)-5-phenyloxazole;2-(4-Biphenyl)-5-phenyloxazole;5-phenyl-2-(4-phenylphenyl)-1,3-oxazole;2-(4-Biphenylyl)-5-phenyloxazole;S5HT3RX97E;EINECS 212-711-5;NSC-87971;2-([1,1'-Biphenyl]-4-yl)-5-phenyloxazole;Oxazole, 2-[1,1'-biphenyl]-4-yl-5-phenyl-;Oxazole, 2-(1,1'-biphenyl)-4-yl-5-phenyl-;NSC87971;2-Diphenyl-5-phenyloxazol;UNII-S5HT3RX97E;CBDivE_006435;SCHEMBL2684521;2-p-Biphenylyl-5-phenyloxazole;DTXSID50234393;5-Phenyl-2-(4-biphenylyl)oxazole;CCG-16010;NSC 87971;AKOS001595170;2-(4-Biphenyl)-5-phenyloxazole 98;Oxazole, 2-(4-Biphenylyl)-5-phenyl-;2-(4-Biphenyl)-5-phenyloxazole, 98%;2-[1,1'-Biphenyl]-4-yl-5-phenyloxazole;EU-0003393;FT-0608588;2-(1,1'-biphenyl-4-yl)-5-phenyl-1,3-oxazole;2-[1,1'-Biphenyl]-4-yl-5-phenyl-1,3-oxazole #

Chemical Property of 2-(Biphenyl-4-yl)-5-phenyloxazole

Chemical Property:

• Vapor Pressure: 3.63E-09mmHg at 25°C
• Melting Point: 115-119oC(lit.)
• Boiling Point: 487.1°Cat760mmHg
• Flash Point: 209.7°C
• PSA: 26.03000
• Density: 1.137g/cm³
• LogP: 5.67560
• Storage Temp.: ?20°C
• XLogP3: 6.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 297.115364102
• Heavy Atom Count: 23
• Complexity: 351

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(4-Biphenyl)-5-phenyloxazole 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-36
• Safety Statements: 26-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C3=NC=C(O3)C4=CC=CC=C4

Technology Process of 2-(Biphenyl-4-yl)-5-phenyloxazole

There total 3 articles about 2-(Biphenyl-4-yl)-5-phenyloxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C22H15NO3 → 2-(4-biphenylyl)-5-phenyloxazole (852-37-9)

Guidance literature:

With fac-tris(2-phenylpyridinato-N,C₂')iridium(III); In 1,4-dioxane; at 20 ℃; for 3h; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.9b00903

Reference yield:

N-(2-oxo-2-phenylethyl)-4-phenylbenzamide (37061-74-8) → 2-(4-biphenylyl)-5-phenyloxazole (852-37-9)

Guidance literature:

With trichlorophosphate;

DOI:10.1021/ja01612a041

Reference yield:

→ 2-(4-biphenylyl)-5-phenyloxazole (852-37-9)

Guidance literature:

(p-Phenyl-benzoylaminomethyl)-phenyl-keton, POCl3, Erhitzen;

DOI:10.1016/0040-4020(63)80019-8

upstream raw materials:

N-(2-oxo-2-phenylethyl)-4-phenylbenzamide

Downstream raw materials:

3-<2-(4-biphenylyl)-5-phenyloxazolio-3>propanesulfonate

4-(5-phenyl-2-oxazolyl)-4'-<5-(4-biphenylyl)-2-oxazolyl>diphenylmethane

bis[2-(biphenyl-4-yl-3-ido)-5-phenyloxazole]ethylenediaminerhodium(III) chloride

3-propane potassium sulfonate

Refernces