2-Hydroxychalcone

Base Information Edit

Chemical Name:2-Hydroxychalcone
CAS No.:644-78-0
Molecular Formula:C15H12O2
Molecular Weight:224.259
Hs Code.:29147000
European Community (EC) Number:211-422-1,624-468-6
NSC Number:640539,170281,37432
Nikkaji Number:J400.833B,J95.421G
Metabolomics Workbench ID:73727
ChEMBL ID:CHEMBL147067
Mol file:644-78-0.mol

Synonyms:2-Hydroxychalcone;644-78-0;3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one;42224-53-3;(E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one;(2E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one;(E)-2-Hydroxychalcone;Salicylalacetophenone;2-(2-Hydroxybenzal)acetophenone;MLS002608038;2-Hydroxybenzylidene acetophenone;2-Propen-1-one, 3-(2-hydroxyphenyl)-1-phenyl-;EINECS 211-422-1;NSC640539;NSC 640539;AI3-00855;3-(2-hydroxyphenyl)-1-phenyl-2-propen-1-one;(E)-3-(2-hydroxyphenyl)-1-phenyl-prop-2-en-1-one;Chalcone, 1;2-Hydroxychalcone, 95%;SCHEMBL626785;SCHEMBL626787;CHEMBL147067;BDBM86002;6-[(1Z,2Z)-3-Hydroxy-3-phenyl-2-propene-1-ylidene]-2,4-cyclohexadiene-1-one;UDOOPSJCRMKSGL-ZHACJKMWSA-N;HMS3078L22;NSC37432;2-(2-Hydroxybenzylidene)acetophenone;MFCD00016449;NSC-37432;NSC170281;STK093271;AKOS000486194;AKOS025309995;NSC-170281;NSC-640539;MS-10592;SMR001526790;HY-119931;CS-0078796;CS-0311212;H0234;A834764;AB-016/30005051;SR-01000078236;SR-01000078236-1;trans-3-(O-Hydroxyphenyl)-1-phenyl-2-propen-1-one;W-104837;(2E)-3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one #

Suppliers and Price of 2-Hydroxychalcone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxychalcone
500mg
$ 75.00

TCI Chemical
2-Hydroxychalcone >98.0%(GC)(T)
25g
$ 148.00

TCI Chemical
2-Hydroxychalcone >98.0%(GC)(T)
5g
$ 54.00

SynQuest Laboratories
2-Hydroxychalcone 98%
5 g
$ 79.00

SynQuest Laboratories
2-Hydroxychalcone 98%
1 g
$ 20.00

Aronis compounds
3-(2-hydroxyphenyl)-1-phenyl-2-propen-1-one
5mg
$ 15.00

American Custom Chemicals Corporation
(E)-3-(2-HYDROXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE 95.00%
25G
$ 500.00

American Custom Chemicals Corporation
(E)-3-(2-HYDROXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE 95.00%
5G
$ 430.00

American Custom Chemicals Corporation
(E)-3-(2-HYDROXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE 95.00%
1G
$ 406.00

Ambeed
3-(2-Hydroxyphenyl)-1-phenylprop-2-en-1-one 98%
5g
$ 20.00

Total 33 raw suppliers

Chemical Property of 2-Hydroxychalcone Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:144-150 °C(lit.)
Refractive Index:1.654
Boiling Point:396.3 °C at 760 mmHg
PKA:9.26±0.35(Predicted)
Flash Point:169.3 °C
PSA：37.30000
Density:1.191 g/cm³
LogP:3.28830
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:224.083729621
Heavy Atom Count:17
Complexity:277

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Hydroxychalcone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C=CC2=CC=CC=C2O
Isomeric SMILES:C1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2O
Description 2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB.

Technology Process of 2-Hydroxychalcone

There total 32 articles about 2-Hydroxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%