2-Bromo-2-ethylbutyramide

Base Information

• Chemical Name: 2-Bromo-2-ethylbutyramide
• CAS No.: 511-70-6
• Molecular Formula: C6H12 Br N O
• Molecular Weight: 194.071
• Hs Code.: 2924199090
• European Community (EC) Number: 208-132-2
• NSC Number: 4607
• UNII: 6BTQ2OHW47
• DSSTox Substance ID: DTXSID80199108
• Nikkaji Number: J6.269C
• Wikidata: Q27264457
• Mol file: 511-70-6.mol

Synonyms:carbromide

Chemical Property of 2-Bromo-2-ethylbutyramide

Chemical Property:

• Vapor Pressure: 0.0115mmHg at 25°C
• Melting Point: 67°
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 261.6°Cat760mmHg
• PKA: 14.93±0.50(Predicted)
• Flash Point: 112°C
• PSA: 43.09000
• Density: 1.37g/cm³
• LogP: 2.12570
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 193.01023
• Heavy Atom Count: 9
• Complexity: 110

Purity/Quality:

99%min ^*data from raw suppliers

DIETHYLBROMOACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(CC)(C(=O)N)Br

Technology Process of 2-Bromo-2-ethylbutyramide

There total 9 articles about 2-Bromo-2-ethylbutyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethyl-2-bromo-butyryl chloride (74988-02-6) → 2-bromo-2-ethylbutanamide (511-70-6)

Guidance literature:

With ammonia;

Reference yield:

→ 2-bromo-2-ethylbutanamide (511-70-6)

Guidance literature:

at 110 ℃; im Valuum;

Reference yield:

2-ethyl-butyronitrile (617-80-1) → 2-bromo-2-ethylbutanamide (511-70-6)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine

With bromine;

upstream raw materials:

2-ethyl-2-bromo-butyronitrile

2-ethylbutanamide

2-ethyl-2-bromo-butyryl chloride

ethyl 2-bromo-2-ethylbutanoate

Downstream raw materials:

2-ethyl-2-hydroxybutyric acid

pentan-3-one

2-Ethylmercapto-2-ethyl-buttersaeure-amid

hydrogen cyanide