1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione

Base Information

• Chemical Name: 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione
• CAS No.: 554-34-7
• Molecular Formula: C18H18 O6
• Molecular Weight: 330.337
• Mol file: 554-34-7.mol

Synonyms:Ethanedione,bis(3,4-dimethoxyphenyl)- (9CI); Veratril (6CI,8CI);3,3',4,4'-Tetramethoxybenzil; NSC 16733

Chemical Property of 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione

Chemical Property:

• Vapor Pressure: 2.39E-10mmHg at 25°C
• Boiling Point: 505.6°Cat760mmHg
• Flash Point: 223.6°C
• PSA: 71.06000
• Density: 1.195g/cm³
• LogP: 2.78660

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione

There total 45 articles about 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-[(3,4-dimethoxyphenyl)ethynyl]-1,2-dimethoxybenzene (79238-81-6) → 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione (554-34-7)

Guidance literature:

With potassium permanganate; sodium hydrogencarbonate; magnesium sulfate; In water; acetone; at 20 ℃; for 24h;

DOI:10.1021/ol300948u

Reference yield: 90.0%

3,3',4,4'-tetramethoxybenzoin (5653-60-1) → 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione (554-34-7)

Guidance literature:

With hydrogen bromide; dimethyl sulfoxide; In water; at 50 - 90 ℃;

DOI:10.1016/j.tetlet.2013.01.095

Reference yield: 81.0%

1,2-bis(3,4-dimethoxyphenyl)ethanone (4927-55-3) → 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione (554-34-7)

Guidance literature:

With selenium(IV) oxide; In 1,4-dioxane; water; for 15h; Reflux;

DOI:10.1039/c1cc11717c

upstream raw materials:

oxalyl dichloride

1,2-dimethoxybenzene

3,3',4,4'-tetramethoxybenzoin

methanol

Downstream raw materials:

7-hydroxy-2,3-bis(3,4-dimethoxyphenyl)-6-quinoxalinecarboxylic acid

5,6-bis-(3,4-dimethoxy-phenyl)-3-methylsulfanyl-[1,2,4]triazine

2,3-bis(3,4-dimethoxyphenyl)-6-quinoxalinecarboxylic acid

3,4,3',4'-tetramethoxy-benzilic acid

Refernces

• 1、 Aydin, Engin Aytac,Altenbach, Hans-Josef. "Fluorogenic Diels-Alder reactions of novel phencyclone derivatives". supporting information. p. 1832 - 1834. Retrieved 2013/05/08.
• 2、 Short, Rhys,Carta, Mariolino,Bezzu, C. Grazia,Fritsch, Detlev,Kariuki, Benson M.,McKeown, Neil B.. "Hexaphenylbenzene-based polymers of intrinsic microporosity". supporting information; experimental part. p. 6822 - 6824. Retrieved 2011/08/08.