3β,22α-Dihydroxyolean-12-en-29-oic acid

Base Information

• Chemical Name: 3β,22α-Dihydroxyolean-12-en-29-oic acid
• CAS No.: 84108-17-8
• Molecular Formula: C₃₀H₄₈O₄
• Molecular Weight: 472.709
• Mol file: 84108-17-8.mol

Synonyms:Maytenfolic acid;Olean-12-en-29-oic acid,3,22-dihydroxy-,(3a,20R,22R)-;

Chemical Property of 3β,22α-Dihydroxyolean-12-en-29-oic acid

Chemical Property:

• Vapor Pressure: 4.48E-16mmHg at 25°C
• Refractive Index: 1.568
• Boiling Point: 584.1 °C at 760 mmHg
• Flash Point: 321.1 °C
• PSA: 77.76000
• Density: 1.14 g/cm³
• LogP: 6.20440

Purity/Quality:

98%min ^*data from raw suppliers

TriptotriterpenicacidA 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3β,22α-Dihydroxyolean-12-en-29-oic acid

There total 1 articles about 3β,22α-Dihydroxyolean-12-en-29-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

wilforlide A (84104-71-2) → 3β,22α-dihydroxy-olean-12-en-29α-oic acid (84108-17-8,100897-87-8)

Guidance literature:

With sodium hydroxide; In methanol; ethanol;

DOI:10.1039/c39820001197

Reference yield:

3β,22α-dihydroxy-olean-12-en-29α-oic acid (84108-17-8,100897-87-8) → wilforlide A (84104-71-2)

Guidance literature:

With sulfuric acid; In ethanol; for 2h; Heating;

DOI:10.1039/c39820001048

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 3β,22α-dihydroxy-olean-12-en-29α-oic acid (84108-17-8,100897-87-8) → Methyl-3β,22α-dihydroxyolean-12-en-29-oate (84104-83-6)

Guidance literature:

In diethyl ether; Ambient temperature;

DOI:10.1139/v92-182

upstream raw materials:

wilforlide A

Downstream raw materials:

Methyl-3β,22α-dihydroxyolean-12-en-29-oate

wilforlide A

Refernces