2-Isopropoxypropane

Base Information

• Chemical Name: 2-Isopropoxypropane
• CAS No.: 108-20-3
• Molecular Formula: C6H14O
• Molecular Weight: 102.177
• Hs Code.: 2909199090
• European Community (EC) Number: 203-560-6
• ICSC Number: 0906
• UN Number: 1159
• UNII: DO7Y998826
• DSSTox Substance ID: DTXSID4021890
• Nikkaji Number: J5.069E
• Wikipedia: Diisopropyl_ether
• Wikidata: Q418989
• ChEMBL ID: CHEMBL3185565
• Mol file: 108-20-3.mol

Synonyms:Isopropylether (8CI);2,2'-Oxybispropane;2-Isopropoxypropane;Bis(isopropyl) ether;Di-1-methylethyl ether;Diisopropyl ether;Diisopropyl oxide;iso-Propyl ether;Propane, 2,2'-oxybis-;

Chemical Property of 2-Isopropoxypropane

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 152mmHg at 25°C
• Melting Point: -85.5 °C
• Refractive Index: n20/D 1.367(lit.)
• Boiling Point: 68.3 °C at 760 mmHg
• Flash Point: −29°F
• PSA: 9.23000
• Density: 0.758 g/cm³
• LogP: 1.81980
• Water Solubility.: 9 g/L (20℃)
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 102.104465066
• Heavy Atom Count: 7
• Complexity: 33.4
• Transport DOT Label: Flammable Liquid

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F:Flammable
• Statements: R11:; R19:; R66:; R67:
• Safety Statements: S16:; S29:; S33:; S9:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Ethers (
• Canonical SMILES: CC(C)OC(C)C
• Inhalation Risk: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. Exposure above the OEL could cause lowering of consciousness.
• Effects of Long Term Exposure: Repeated or prolonged contact with skin may cause dermatitis.

Technology Process of 2-Isopropoxypropane

There total 132 articles about 2-Isopropoxypropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

carbon monoxide (201230-82-2) + isopropyl alcohol (67-63-0,8013-70-5) → i-Amyl alcohol (123-51-3) + 2-methyl-propan-1-ol (78-83-1) + di-isopropyl ether (108-20-3) + 1-isopropoxy-2-methyl-propane (78448-33-6)

Guidance literature:

With hydrogen; Cobalt rhodium; iodine; at 200 ℃; for 2h; under 315025 Torr; Product distribution; other promoter, other pressure;

DOI:10.1016/0022-328X(88)80121-9

Reference yield:

isopropyl alcohol (67-63-0,8013-70-5) → diisopropyl hydrogenphosphonate (1809-20-7) + di-isopropyl ether (108-20-3)

Guidance literature:

With oxygen; phosphan; copper(ll) bromide; at 50 ℃; Reagent/catalyst; Temperature; Catalytic behavior; Kinetics; Mechanism;

DOI:10.1134/S0036024416080227

Reference yield:

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → methanol (67-56-1) + propylene glycol (57-55-6,63625-56-9) + methane (34557-54-5,27936-85-2) + ethanol (64-17-5) + di-isopropyl ether (108-20-3) + Dipropyl ether (111-43-3) + carbon dioxide (124-38-9,18923-20-1) + carbon monoxide (201230-82-2) + isopropyl alcohol (67-63-0,8013-70-5) + acetone (67-64-1) + iso-butanol (78-92-2,15892-23-6)

Guidance literature:

With water; 5.1%Pt-4.9%Re/C; 1%Ru/TiO2; at 274.84 ℃; under 3750.38 Torr; Product distribution / selectivity;

upstream raw materials:

2-iodo-propane

propene

isopropyl alcohol

diisopropyl sulfate

Downstream raw materials:

phenyl-piperidin-1-yl-acetaldehyde

cyclotriveratrylene

4-chloro-2-isopropyl-5-methylphenol

methane

Refernces

• 1、 Hernández-Cortez,Manríquez, Ma.,Lartundo-Rojas,López-Salinas. "Study of acid-base properties of supported heteropoly acids in the reactions of secondary alcohols dehydration". . p. 32 - 38. Retrieved 2014.
• 2、 Sánchez-Trinidad, Cecilia,del Angel, Gloria,Torres-Torres, Gilberto,Cervantes-Uribe, Adrián,Pavón, A. Abiu Silahua,Guerra-Que, Zenaida,Arévalo-Pérez, Juan Carlos,Tzompantzi-Morales, Fancisco J.. "Effect of the CuAl2O4 and CuAlO2 Phases in Catalytic Wet Air Oxidation of ETBE and TAME using CuO/γ-Al2O3 catalysts". . p. 1143 - 1150. Retrieved 2019.
• 3、 Polimbetova,Borangazieva,Ibraimova, Zh. U.,Bugubaeva,Keynbay. "Oxidative alkoxylation of phosphine in alcohol solutions of copper halides". . p. 1539 - 1544. Retrieved 2016.
• 4、 Blasco-Jiménez, Davinia,Sobczak, Izabela,Ziolek, Maria,López-Peinado, Antonio J.,Martín-Aranda, Rosa M.. "Amino-grafted metallosilicate MCM-41 materials as basic catalysts for eco-friendly processes". . p. 119 - 125. Retrieved 2010.
• 5、 Rochester, Colin H.,Graham, John,Rudham, Robert. "Infrared Study of the Adsorption of Propan-2-ol on Rutile at the Solid/Vapour and Solid/Heptane Interfaces". . p. 2459 - 2466. Retrieved 1984.
• 6、 Bedia,Ruiz-Rosas,Rodriguez-Mirasol,Cordero. "A kinetic study of 2-propanol dehydration on carbon acid catalysts". . p. 33 - 42. Retrieved 2010.
• 7、 Granger,Giraudon,Delannoy,Leclercq,Leclercq. "Chloropentafluoroethane hydrodechlorination over tungsten carbides: Influence of surface stoichiometry". . p. 358 - 362. Retrieved 2002.
• 8、 Oezkart, Saim,Finke, Richard G.. "Iridium(0) nanocluster, acid-assisted catalysis of neat acetone hydrogenation at room temperature: Exceptional activity, catalyst lifetime, and selectivity at complete conversion". . p. 4800 - 4808. Retrieved 2005.
• 9、 El-Nahas, Safaa,Abdelkader, Adel,Halawy, Samih A.,Mohamed, Mohamed A.. "Nanocrystalline MgO samples (11.5 and 12.6?nm) derived from two different precursors: characterization and catalytic activity". . p. 1313 - 1322. Retrieved 2017.
• 10、 Min, Joon-Seok,Misono, Makoto,Taguchi, Akira,Mizuno, Noritaka. "Remarkable effect of iron-substitution for molybdenum in phosphododecamolybdate on oxidative dehydrogenation of 2-propanol". . p. 28 - 29. Retrieved 2001.