Dihydroaflatoxin G1

Base Information

• Chemical Name: Dihydroaflatoxin G1
• CAS No.: 7241-98-7
• Molecular Formula: C17H14 O7
• Molecular Weight: 330.294
• Hs Code.: 30029090
• Wikidata: Q105309796
• Metabolomics Workbench ID: 44421
• Mol file: 7241-98-7.mol

Synonyms:Dihydroaflatoxin G1;Aflatoxin G2-d3;11-methoxy-6,8,16,20-tetraoxapentacyclo[10.8.0.02,9.03,7.013,18]icosa-1,9,11,13(18)-tetraene-17,19-dione;1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,9,10,10a-hexahydro-5-methoxy-, (7aR-cis)-;1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a.alpha.,9,10,10a.alpha.-hexahydro-5-methoxy-;SCHEMBL935567;WPCVRWVBBXIRMA-UHFFFAOYSA-N;1H,12H-Furo(3',2':4,5)furo(2,3-h)pyrano(3,4-c)(1)benzopyran-1,12-dione, 3,4,7a-alpha,9,10,10a-alpha-hexahydro-5-methoxy-;LS-70762;FT-0621935;11-methoxy-6,8,16,20-tetraoxapentacyclo[10.8.0.0^{2,9}.0^{3,7}.0^{13,18}]icosa-1,9,11,13(18)-tetraene-17,19-dione;5-Methoxy-3,4,7a,9,10,10a-hexahydro-1H,12H-furo[3',2':4,5]furo[2,3-H]pyrano[3,4-c]chromene-1,12-dione #

Chemical Property of Dihydroaflatoxin G1

Chemical Property:

• Melting Point: 237-240oC
• Refractive Index: 1.4790 (estimate)
• Boiling Point: 602.5 °C at 760 mmHg
• Flash Point: 269.6 °C
• PSA: 84.20000
• Density: 1.55 g/cm³
• LogP: 1.73690
• Storage Temp.: 2-8°C
• Water Solubility.: 15mg/L(temperature not stated)
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 1
• Exact Mass: 330.07395278
• Heavy Atom Count: 24
• Complexity: 626

Purity/Quality:

98%,99%, ^*data from raw suppliers

Aflatoxin G2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T+
• Hazard Codes: T+,T,Xn,F
• Statements: 45-26/27/28-36-20/21/22-11-39/23/24/25-23/24/25-65-48/23/24/25-36/38-46
• Safety Statements: 53-28-36/37-45-36-26-16-7-62

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4C5CCOC5OC4=C1
• Uses: Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Aflatoxin G2 is the minor analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed.

Technology Process of Dihydroaflatoxin G1

There total 2 articles about Dihydroaflatoxin G1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ aflatoxin G2 (7241-98-7)

Guidance literature:

aus Aflatoxin G(1) durch kat. Hydrierung;

DOI:10.1021/jf60153a019

Reference yield:

aflatoxin G1 (1165-39-5) → aflatoxin G2 (7241-98-7)

Guidance literature:

With hydrogenchloride; sodium hydroxide; LACTIC ACID; at 37 ℃; pH=3.35 - 4.50; Further Variations:; reagents concentration; Kinetics;

DOI:10.1016/S0960-894X(02)00533-4

upstream raw materials:

aflatoxin G₁

Refernces

• 1、 Shukla, Ram S.,Verma, Ramtej J.,Mehta, Daxa N.. "Kinetic and mechanistic investigations on reductions of aflatoxins by lactic acid". . p. 2737 - 2741. Retrieved 2007/10/03.