MeOPN

Base Information

• Chemical Name: MeOPN
• CAS No.: 2697-42-9
• Molecular Formula: C2H8 N O3 P
• Molecular Weight: 125.064
• Hs Code.: 2929909090
• Mol file: 2697-42-9.mol

Synonyms:Methylphosphoramidate (6CI); Dimethyl aminophosphonate; Dimethyl phosphoramidate

Chemical Property of MeOPN

Chemical Property:

• Vapor Pressure: 0.00132mmHg at 25°C
• Boiling Point: 297.8°Cat760mmHg
• Flash Point: 133.9°C
• PSA: 71.36000
• Density: 1.224g/cm³
• LogP: 1.04630

Purity/Quality:

97% ^*data from raw suppliers

DIMETHYL PHOSPHORAMIDATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of MeOPN

There total 8 articles about MeOPN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

4-fluoro-β-nitrostyrene (5153-69-5,706-08-1) + phosphorous acid trimethyl ester (121-45-9) → phosphoramidic acid dimethyl ester (2697-42-9) + dimethyl <1-(p-fluorophenyl)vinyl>phosphonate (81487-70-9) + dimethyl <1-(p-fluorophenyl)-2-nitroethyl>phosphonate (81487-71-0)

Guidance literature:

With acetic acid; for 24h;

Reference yield:

methanol (67-56-1) + tetraamidophosphonium chloride → trimethyl phosphite (512-56-1) + dimethylphosphoric acid (813-78-5) + phosphoramidic acid dimethyl ester (2697-42-9) + Diamidophosphorsaeuremethylester (22457-53-0) + phosphoramide (25758-26-3,13597-72-3) + 1,1,1,3,3,3-hexaamino-1λ(5),3λ(5)-diphosphazenium chloride

Guidance literature:

at 60 ℃; methanolysis;

Reference yield:

methanol (67-56-1) + 1,1,1,3,3,3-hexaamino-1λ(5),3λ(5)-diphosphazenium chloride → methylphosphate (812-00-0) + phosphoramidic acid dimethyl ester (2697-42-9) + phosphoramide (25758-26-3,13597-72-3)

Guidance literature:

for 16h; Heating; methanolysis;

upstream raw materials:

methanol

diphenylphosphoroamidate

2-(2-nitrovinyl)furan

phosphorous acid trimethyl ester

Downstream raw materials:

(2-(pyridin-2-yl)-5-trifluoromethylphenyl)carbamic acid 4-(dimethoxyphosphorylaminocarbonyl)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^4,6]octadec-7-en-17-yl ester

Refernces

• 1、 Vafina, N. M.,Efremov, Yu. Ya.,Zyablikova, T. A.,Il'yasov, A. V.,Shermergorn, I. M.. "REACTIONS OF 2-(2-NITROVINYL)FURAN WITH TRIALKYL PHOSPHITES". . p. 2236 - 2242. Retrieved 2007/10/02.
• 2、 Kasparek, Frantisek,Mollin, Jiri. "SOLVOLYSIS OF DIPHENYL AMIDOPHOSPHATES IN AQUEOUS ALCOHOLIC MEDIA". . p. 386 - 396. Retrieved 2007/10/02.