Ethanone, 1-(3,4-dihydro-6-methyl-2H-pyran-2-yl)-

Base Information

• Chemical Name: Ethanone, 1-(3,4-dihydro-6-methyl-2H-pyran-2-yl)-
• CAS No.: 28450-02-4
• Molecular Formula: C8H12O2
• Molecular Weight: 140.182
• Hs Code.: 2932999099
• Mol file: 28450-02-4.mol

Synonyms:Ketone,3,4-dihydro-6-methyl-2H-pyran-2-yl methyl (6CI,7CI,8CI);2-Acetyl-3,4-dihydro-6-methyl-2H-pyran;2-Acetyl-6-methyl-2,3-dihydro-4H-pyran;

Chemical Property of Ethanone, 1-(3,4-dihydro-6-methyl-2H-pyran-2-yl)-

Chemical Property:

• Vapor Pressure: 0.13mmHg at 25°C
• Refractive Index: 1.457
• Boiling Point: 217.9 °C at 760 mmHg
• Flash Point: 86.8 °C
• PSA: 26.30000
• Density: 1.001 g/cm³
• LogP: 1.65820

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: Ethanone, 1-(3,4-dihydro-6-methyl-2H-pyran-2-yl)-, is a chemical compound with applications in various fields. In the field of fragrance and perfumery, it is used as a key component in the formulation of scents and fragrances, contributing to the creation of pleasant and unique aromas. Its role is pivotal in enhancing the olfactory appeal of perfumes, colognes, and other scented products. Additionally, in organic chemistry and chemical research, this compound can serve as a building block for the synthesis of complex organic molecules, aiding in the development of new fragrances and specialty chemicals. Furthermore, it may find applications in the food and beverage industry as a flavoring agent, contributing to the creation of food products with distinctive and appealing tastes. Its versatile utility underscores its significance in advancing perfumery, organic chemistry, and the culinary arts, where it plays a crucial role in sensory experiences, chemical synthesis, and flavor enhancement.

Technology Process of Ethanone, 1-(3,4-dihydro-6-methyl-2H-pyran-2-yl)-

There total 17 articles about Ethanone, 1-(3,4-dihydro-6-methyl-2H-pyran-2-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-methylcyclohexane-1,3-dione (1193-55-1) + methyl vinyl ketone (78-94-4,25038-87-3) → 2-methyl-2-(3-oxobutyl)cyclohexane-1,3-dione (5073-65-4) + Wieland-Miescher ketone (20007-99-2,33878-99-8,100348-93-4,20007-72-1) + 2-acetyl-6-methyl-2,3-dihydropyran (28450-02-4)

Guidance literature:

magnesium oxide; at 100 ℃; for 2h; under 75007.5 Torr;

DOI:10.1016/j.tetlet.2004.04.146

Reference yield: 65.0%

2-acetyl-2,5-bis(phenylthio)-6-methyl-3,4-dihydropyran (19718-58-2) → 2-acetyl-6-methyl-2,3-dihydropyran (28450-02-4)

Guidance literature:

With ethanol; nickel; for 8h; Heating;

DOI:10.1021/jo00346a012

Reference yield: 60.0%

methyl vinyl ketone (78-94-4,25038-87-3) → 2-acetyl-6-methyl-2,3-dihydropyran (28450-02-4)

Guidance literature:

With hydroquinone; at 145 ℃; for 24h;

DOI:10.1016/S0040-4020(01)81519-2

upstream raw materials:

3-buten-1-yne

methyl vinyl ketone

2-acetyl-2,5-bis(phenylthio)-6-methyl-3,4-dihydropyran

(Z)-1-Chloro-2,3-diiodobutadiene

Downstream raw materials:

C₉H₁₃⁽²⁾H₃O₂

1-(6-Methyl-3,4-dihydro-2H-pyran-2-yl)-undecan-1-one

exo-7-(3-methoxyphenyl)-5,7-dimethyl-6,8-dioxabicyclo<3.2.1>octane

endo-7-(3-methoxyphenyl)-5,7-dimethyl-6,8-dioxabicyclo<3.2.1>octane

Refernces

• 1、 Suslov,Korchagina,Volcho,Salakhutdinov. "Synthesis of heterocyclic compounds using basic zeolite Csβ". . p. 560 - 566. Retrieved 2009.
• 2、 Wang, Zhihong,Hirschi, Jennifer S.,Singleton, Daniel A.. "Recrossing and dynamic matching effects on selectivity in a diels-alder reaction". supporting information; experimental part. p. 9156 - 9159. Retrieved 2010/03/03.
• 3、 Jun, Jong-Gab,Kim, Ae-Ran,Sung, Hoon Kim. "Study on the functionalization and reactivity of bicyclic acetal compounds". . p. 45 - 52. Retrieved 2007/10/03.