1,3,5-Trinitro-2-piperidinobenzene

Base Information

• Chemical Name: 1,3,5-Trinitro-2-piperidinobenzene
• CAS No.: 67263-27-8
• Molecular Formula: C11H12N4O6
• Molecular Weight: 296.239
• Mol file: 67263-27-8.mol

Synonyms:1-Picryl-piperidin;1-picryl-piperidine;2,4,6-trinitro-1-piperidinobenzene;

Chemical Property of 1,3,5-Trinitro-2-piperidinobenzene

Chemical Property:

• PSA: 140.70000
• LogP: 4.03610

Purity/Quality:

1-(2,4,6-TRINITROPHENYL)PIPERIDINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3,5-Trinitro-2-piperidinobenzene

There total 18 articles about 1,3,5-Trinitro-2-piperidinobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.3%

piperidine (110-89-4) + 4-Dimethylamino-1-(2,4,6-trinitro-phenyl)-pyridinium; chloride (111055-14-2) → 2,4,6-trinitro-1-piperidinobenzene (67263-27-8)

Guidance literature:

In acetonitrile; for 24h; Ambient temperature;

Reference yield: 61.0%

piperidine (110-89-4) + 2,4,6-trinitrochlorobenzene (88-88-0) → 2,4,6-trinitro-1-piperidinobenzene (67263-27-8)

Guidance literature:

In dimethyl sulfoxide;

DOI:10.1016/S0040-4020(01)87755-3

Reference yield:

piperidine (110-89-4) + picryl-p-tolyl sulfide (51030-13-8) → 2,4,6-trinitro-1-piperidinobenzene (67263-27-8) + para-thiocresol (106-45-6)

Guidance literature:

With n-butylammonium perchlorate; In dimethyl sulfoxide; at 25 ℃; Rate constant; var. conc. of reagents;

upstream raw materials:

piperidine

2,4,6-trinitrochlorobenzene

bis(2,4,6-trinitrophenyl) sulfone

1-methoxy-2,4,6-trinitrobenzene

Downstream raw materials:

N-ethyl-2,4,6-trinitroaniline

N-butyl-2,4,6-trinitroaniline

N-methylpicramide

N?isopropyl?2,4,6?trinitroaniline

Refernces

• 1、 Ormazabal-Toledo, Rodrigo,Santos, Jose G.,Rios, Paulina,Castro, Enrique A.,Campodonico, Paola R.,Contreras, Renato. "Hydrogen bond contribution to preferential solvation in SNAr reactions". . p. 5908 - 5915. Retrieved 2013/07/25.
• 2、 Crampton, Michael R.,Emokpae, Thomas A.,Isanbor, Chukwuemeka,Batsanov, Andrei S.,Howard, Judith A. K.,Mondal, Raju. "Effects of ortho- and para-ring activation on the kinetics of S NAr reactions of 1-chloro-2-nitro- and 1-phenoxy-2-nitrobenzenes with aliphatic amines in acetonitrile". . p. 1222 - 1230. Retrieved 2007/10/03.