N-(3,4-Dichlorophenyl)glycine

Base Information

• Chemical Name: N-(3,4-Dichlorophenyl)glycine
• CAS No.: 65051-17-4
• Molecular Formula: C8H7 Cl2 N O2
• Molecular Weight: 220.0527
• Hs Code.: 2922499990
• Mol file: 65051-17-4.mol

Synonyms:(3,4-Dichlorophenylamino)aceticacid; N-(3,4-Dichlorophenyl)glycine; NSC 520114

Chemical Property of N-(3,4-Dichlorophenyl)glycine

Chemical Property:

• Vapor Pressure: 5.26E-09mmHg at 25°C
• Melting Point: 141-142 °C
• Boiling Point: 453.3°Cat760mmHg
• PKA: 3.75±0.40(Predicted)
• Flash Point: 227.9°C
• PSA: 49.33000
• Density: 1.528g/cm³
• LogP: 2.56290

Purity/Quality:

98.5% ^*data from raw suppliers

2-((3,4-Dichlorophenyl)amino)aceticacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(3,4-Dichlorophenyl)glycine

There total 6 articles about N-(3,4-Dichlorophenyl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

m,p-dichloroaniline (95-76-1) → (3,4-Dichloroanilino)-acetic acid (65051-17-4)

Guidance literature:

With hydrogenchloride; sodium acetate; sodium carbonate; chloroacetic acid; In water; acetic acid;

Reference yield:

ethyl 2-((3,4-dichlorophenyl)amino)acetate (14108-81-7) → (3,4-Dichloroanilino)-acetic acid (65051-17-4)

Guidance literature:

With water; lithium hydroxide; for 1.5h; Reflux;

DOI:10.1016/j.bioorg.2021.105196

Reference yield:

chloroacetic acid (79-11-8) + m,p-dichloroaniline (95-76-1) → (3,4-Dichloroanilino)-acetic acid (65051-17-4)

Guidance literature:

With sodium acetate; acetic acid;

DOI:10.1007/BF02762719

upstream raw materials:

<(3,4-dichlorophenyl)amino>acetonitrile

chloroacetic acid

m,p-dichloroaniline

formaldehyd

Downstream raw materials:

ethyl 2-((3,4-dichlorophenyl)amino)acetate

1-(3,4-dichlorophenyl)-3,4-bis(hydroxymethyl)pyrazole bis(methylcarbamate)

dimethyl 1-(3,4-dichlorophenyl)pyrazole-3,4-dicarboxylate

1-(3,4-dichlorophenyl)-3,4-bis(hydroxymethyl)pyrazole

Refernces

• 1、 -. "NOVEL HETEROCYCLYL COMPOUNDS". Page/Page column 25. . Retrieved 2010/02/17.