Pyridindolol

Base Information

• Chemical Name: Pyridindolol
• CAS No.: 55812-46-9
• Molecular Formula: C₁₄H₁₄N₂O₃
• Molecular Weight: 258.277
• Hs Code.: 2933990090
• NSC Number: 266530
• Wikidata: Q105282825
• Metabolomics Workbench ID: 99961
• ChEMBL ID: CHEMBL1965306
• Mol file: 55812-46-9.mol

Synonyms:1-(1(R),2-dihydroxyethyl)-3-hydroxymethyl-9H-pyrido(3,4-b)indole;pyridindolol;pyridindolol monohydrobromide;pyridindolol monohydrochloride

Chemical Property of Pyridindolol

Chemical Property:

• Vapor Pressure: 1.86E-15mmHg at 25°C
• Boiling Point: 604.3°Cat760mmHg
• Flash Point: 319.3°C
• PSA: 89.37000
• Density: 1.505g/cm³
• LogP: 1.23410
• XLogP3: 0
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 258.10044231
• Heavy Atom Count: 19
• Complexity: 315

Purity/Quality:

99%min ^*data from raw suppliers

PYRIDINDOLOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(N2)C(=NC(=C3)CO)C(CO)O

Technology Process of Pyridindolol

There total 18 articles about Pyridindolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

16-O-acetylpyridindolol (189756-51-2) → pyridindolol (55812-46-9)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 1h;

DOI:10.1021/jo0105585

Reference yield: 91.0%

(R)-(1-(2,2-dimethyl-1,3-dioxolan-4-yl)-9H-pyrido[3,4-b]indol-3-yl)methanol (1443051-70-4) → pyridindolol (55812-46-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; for 2h;

DOI:10.1016/j.tetasy.2013.04.009

Reference yield: 80.0%

methanol (67-56-1) + sodium methylate (124-41-4) + 15,16-O-diacetylpyridindolol (189756-49-8) → pyridindolol (55812-46-9)

Guidance literature:

In methanol; at 25 ℃; for 1h;

DOI:10.7164/antibiotics.50.189

upstream raw materials:

methanol

sodium methylate

16-O-acetylpyridindolol

15,16-O-diacetylpyridindolol

Refernces

• 1、 Kim, Yong-Pil,Takamatsu, Satoshi,Hayashi, Masahiko,Komiyama, Kanki,Omura, Satoshi. "Pyridindolols K1 and K2, new alkaloids from Streptomyces sp. K93-0711". . p. 189 - 193. Retrieved 1997.