Sulfamoyldapsone

Base Information

• Chemical Name: Sulfamoyldapsone
• CAS No.: 17615-73-5
• Molecular Formula: C12H13 N3 O4 S2
• Molecular Weight: 327.385
• Hs Code.: 2935009090
• UNII: LXU2HPW98X
• DSSTox Substance ID: DTXSID90170089
• Nikkaji Number: J31.811F
• Wikidata: Q27155581
• Mol file: 17615-73-5.mol

Synonyms:2-sulfamoyl-4,4'-diaminodiphenyl sulfone;SDDS;sulfamoyldapsone

Chemical Property of Sulfamoyldapsone

Chemical Property:

• Vapor Pressure: 1.12E-18mmHg at 25°C
• Refractive Index: 1.6390 (estimate)
• Boiling Point: 686.1°Cat760mmHg
• Flash Point: 368.7°C
• PSA: 163.10000
• Density: 1.549g/cm³
• LogP: 4.35550
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 3
• Exact Mass: 327.03474825
• Heavy Atom Count: 21
• Complexity: 556

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)S(=O)(=O)C2=C(C=C(C=C2)N)S(=O)(=O)N

Technology Process of Sulfamoyldapsone

There total 10 articles about Sulfamoyldapsone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(N-acetyl-sulfanilyl)-5-amino-benzenesulfonic acid amide (24573-60-2) → 5-amino-2-sulfanilyl-benzenesulfonic acid amide (17615-73-5)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jo01148a027

Reference yield:

2-(N-acetyl-sulfanilyl)-5-nitro-benzenesulfonic acid amide (25006-65-9) → 5-amino-2-sulfanilyl-benzenesulfonic acid amide (17615-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Raney nickel; 1-ethoxy-ethanol-⁽²⁾ / Hydrogenation

2: aqueous hydrochloric acid

With hydrogenchloride; 1-ethoxyethanol; nickel;

DOI:10.1021/jo01148a027

Reference yield:

→ 5-amino-2-sulfanilyl-benzenesulfonic acid amide (17615-73-5)

Guidance literature:

With ethanol; nickel; at 80 ℃; Hydrogenation;

upstream raw materials:

2-(N-acetyl-sulfanilyl)-5-amino-benzenesulfonic acid amide

5-acetylamino-2-(N-acetyl-sulfanilyl)-benzenesulfonic acid amide

S-[4-(acetylamino)phenyl] ethanethioate

2-(N-acetyl-sulfanilyl)-5-nitro-benzenesulfonic acid amide

Downstream raw materials:

acetyl-(5-amino-2-sulfanilyl-benzenesulfonyl)-amine

Refernces