2-Thienylmethyl salicylate

Base Information

• Chemical Name: 2-Thienylmethyl salicylate
• CAS No.: 67443-53-2
• Molecular Formula: C12H10O3S
• Molecular Weight: 234.276
• DSSTox Substance ID: DTXSID401300049
• Mol file: 67443-53-2.mol

Synonyms:2-thienylmethyl salicylate;2-thenyl salicylate;67443-53-2;SCHEMBL3944177;2-Thienylmethyl 2-hydroxybenzoate;DTXSID401300049;2-hydroxy-benzoic acid thiophen-2-yl-methyl ester

Chemical Property of 2-Thienylmethyl salicylate

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 234.03506535
• Heavy Atom Count: 16
• Complexity: 244

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)OCC2=CC=CS2)O

Technology Process of 2-Thienylmethyl salicylate

There total 3 articles about 2-Thienylmethyl salicylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-thiophenemethanol (636-72-6) + methyl salicylate (119-36-8,8024-54-2) → 2-hydroxy-benzoic acid thiophen-2-ylmethyl ester (67443-53-2)

Guidance literature:

sodium methylate; at 95 ℃; for 12h;

Reference yield:

2-Chloromethylthiophene (765-50-4) + sodium salicylate (54-21-7) → 2-hydroxy-benzoic acid thiophen-2-ylmethyl ester (67443-53-2)

Guidance literature:

With triethylamine;

Reference yield:

→ 2-hydroxy-benzoic acid thiophen-2-ylmethyl ester (67443-53-2)

Guidance literature:

Aus o-(2-Thenyloxy)-benzoesaeure (26);

upstream raw materials:

2-Chloromethylthiophene

sodium salicylate

2-thiophenemethanol

methyl salicylate

Refernces