Swertianin

Base Information

• Chemical Name: Swertianin
• CAS No.: 20882-75-1
• Molecular Formula: C14H10O6
• Molecular Weight: 274.23
• Hs Code.: 2932999099
• UNII: 890WXQ4KC0
• ChEMBL ID: CHEMBL187044
• DSSTox Substance ID: DTXSID60174998
• Metabolomics Workbench ID: 70378
• Nikkaji Number: J16.797E
• NSC Number: 289490
• Wikidata: Q27108364
• Mol file: 20882-75-1.mol

Synonyms:gentiakochianin

Chemical Property of Swertianin

Chemical Property:

• Vapor Pressure: 6.59E-14mmHg at 25°C
• Melting Point: 243℃
• Boiling Point: 576.9°Cat760mmHg
• Flash Point: 226.7°C
• PSA: 100.13000
• Density: 1.586g/cm³
• LogP: 2.07160
• Storage Temp.: 2-8°C
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 274.04773803
• Heavy Atom Count: 20
• Complexity: 386

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,2,8-Trihydroxy-6-methoxy-9H-xanthen-9-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C2C(=C1)OC3=C(C2=O)C(=C(C=C3)O)O)O
• Uses: Swertianine is a xanthone that may have some monoamine oxidase inhibitory activity.

Technology Process of Swertianin

There total 2 articles about Swertianin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl]-1,8-dihydroxy-3-methoxyxanthone (1444411-79-3) → Swertianin (20882-75-1) + L-Rhamnose (3615-41-6,478518-52-4) + D-glucose (50-99-7)

Guidance literature:

With trifluoroacetic acid; In methanol; water; at 60 ℃; for 3h;

DOI:10.1021/np400082g

Reference yield:

7-O-(α-L-rhamnopyranosyl)-8-O-(β-D-glucopyranosyl)-1-hydroxy-3-methoxyxanthone (1444411-81-7) → Swertianin (20882-75-1) + L-Rhamnose (3615-41-6,478518-52-4) + D-glucose (50-99-7)

Guidance literature:

With trifluoroacetic acid; In methanol; water; at 60 ℃; for 3h;

DOI:10.1021/np400082g

upstream raw materials:

7-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl]-1,8-dihydroxy-3-methoxyxanthone

7-O-(α-L-rhamnopyranosyl)-8-O-(β-D-glucopyranosyl)-1-hydroxy-3-methoxyxanthone

Refernces