2-Chlorodibenzofuran

Base Information

• Chemical Name: 2-Chlorodibenzofuran
• CAS No.: 51230-49-0
• Molecular Formula: C12H7ClO
• Molecular Weight: 202.64
• European Community (EC) Number: 622-196-2
• UNII: MGI055773B
• DSSTox Substance ID: DTXSID70891563
• Nikkaji Number: J397.557F
• Wikidata: Q27284015
• ChEMBL ID: CHEMBL344922
• Mol file: 51230-49-0.mol

Synonyms:2-chlorodibenzofuran

Chemical Property of 2-Chlorodibenzofuran

Chemical Property:

• Vapor Pressure: 0.000509mmHg at 25°C
• Melting Point: 100℃
• Refractive Index: 1.703
• Boiling Point: 323 °C at 760 mmHg
• Flash Point: 149.1 °C
• PSA: 13.14000
• Density: 1.329 g/cm³
• LogP: 4.23940
• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 202.0185425
• Heavy Atom Count: 14
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

2-CHLORODIBENZOFURAN Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(O2)C=CC(=C3)Cl
• Uses: 2-Chlorodibenzofuran is a standard used in environmental testing and research such as the formation ofdibenzofurans/dibenzodioxins from waste incinerators and flyash.

Technology Process of 2-Chlorodibenzofuran

There total 36 articles about 2-Chlorodibenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(x)BF4*C12H8ClN2O(1+) → 2-chlorodibenzofuran (51230-49-0)

Guidance literature:

With palladium diacetate; In ethanol; Reflux;

DOI:10.1055/s-0031-1289881

Reference yield: 84.0%

2-(4-chloro-phenoxy)-benzoic acid (6410-65-7) → 2-chlorodibenzofuran (51230-49-0)

Guidance literature:

With acethylacetonato(1,5-cyclooctadiene)rhodium(I); potassium iodide; In acetic anhydride; at 160 ℃; for 10h; Inert atmosphere;

DOI:10.1021/ol4010905

Reference yield: 81.0%

2-(4-Chlorophenoxy)benzene-1-diazonium tetrafluoroborate → 2-chlorodibenzofuran (51230-49-0)

Guidance literature:

With tin(ll) chloride; In water; for 0.25h; Heating;

DOI:10.1021/jo00121a016

upstream raw materials:

dibenzofuran

5-chloro-2-phenoxyaniline

2-(4-chlorophenoxy)aniline

2-hydroxydibenzofuran

Downstream raw materials:

2-chloro-7-nitro-dibenzofuran

dibenzofuran

1,4-dihydro-dibenzofuran

4,4,5,5-tetramethyl-2-{8-oxatricyclo[7.4.0²,⁷,]trideca-1⁽⁹⁾,2,4,6,10,12-hexaen-4-yl}-1,3,2-dioxaborolane

Refernces

• 1、 Cho, Ji Young,Roh, Geum-Bee,Cho, Eun Jin. "Visible-Light-Promoted Synthesis of Dibenzofuran Derivatives". . p. 805 - 811. Retrieved 2018/01/28.
• 2、 Maetani, Shinji,Fukuyama, Takahide,Ryu, Ilhyong. "Rhodium-catalyzed decarbonylative C-H arylation of 2-aryloxybenzoic acids leading to dibenzofuran derivatives". supporting information. p. 2754 - 2757. Retrieved 2013/07/19.