Bromomethyl(methyl)malonic acid

Base Information

• Chemical Name: Bromomethyl(methyl)malonic acid
• CAS No.: 67687-97-2
• Molecular Formula: C5H7BrO4
• Molecular Weight: 211.01100
• Mol file: 67687-97-2.mol

Synonyms:2-Bromomethyl-2-methyl-malonic acid;

Chemical Property of Bromomethyl(methyl)malonic acid

Chemical Property:

• PSA: 74.60000
• LogP: 0.55680

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bromomethyl(methyl)malonic acid

There total 1 articles about Bromomethyl(methyl)malonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Brommethyl-methyl-malonsaeure-di-tert-butylester (67587-04-6) → Brommethyl-methyl-malonsaeure (67687-97-2)

Guidance literature:

With trifluoroacetic acid; at 15 ℃; for 3h;

DOI:10.1002/hlca.19780610509

Reference yield:

Brommethyl-methyl-malonsaeure (67687-97-2) → Brommethyl-methyl-malonsaeure-bis-(5,6-dioxo-hexylester) (60004-37-7)

Guidance literature:

Multi-step reaction with 3 steps

1: PCl₅ / diethyl ether

2: Py / diethyl ether

3: (i) O₃, MeOH, (ii) Me₂S

With pyridine; phosphorus pentachloride; In diethyl ether;

DOI:10.1002/hlca.19780610509

upstream raw materials:

Brommethyl-methyl-malonsaeure-di-tert-butylester

Downstream raw materials:

Brommethyl-methyl-malonsaeure-bis-(5,6-dioxo-hexylester)