Pirbuterol

Base Information

• Chemical Name: Pirbuterol
• CAS No.: 38677-81-5
• Molecular Formula: C12H22Cl2N2O3
• Molecular Weight: 240.2988
• European Community (EC) Number: 253-751-3
• UNII: OG645J8RVW
• DSSTox Substance ID: DTXSID0046937
• Nikkaji Number: J16.427E
• Wikipedia: Pirbuterol
• Wikidata: Q1236526
• NCI Thesaurus Code: C61893
• Pharos Ligand ID: R6XT2USJATD1
• Metabolomics Workbench ID: 43483
• ChEMBL ID: CHEMBL1094966
• Mol file: 38677-81-5.mol

Synonyms:2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-tert-butylamino ethyl)pyridine, dihydrochloride;CP 24315-1;CP-24,314-1;CP-24315-1;Maxair;pirbuterol;pirbuterol acetate;pirbuterol acetate salt;pirbuterol dihydrochloride;pirbuterol sulfate;pyrbuterol

Chemical Property of Pirbuterol

Chemical Property:

• Vapor Pressure: 2.17E-10mmHg at 25°C
• Boiling Point: 489.3°Cat760mmHg
• PKA: pKa 8.01/10.64(H2O,t =25±0.05,I=0.010) (Uncertain)
• Flash Point: 249.7°C
• PSA: 85.61000
• Density: 1.196g/cm³
• LogP: 1.09190
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 240.14739250
• Heavy Atom Count: 17
• Complexity: 230

Purity/Quality:

98% min ^*data from raw suppliers

PIRBUTEROL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)NCC(C1=NC(=C(C=C1)O)CO)O
• Uses: Bronchodilator. This relatively selective β2-adrenergic receptor agonist is structurally very similar to albuterol, and it displays similar broncholytic properties. It is used as an inhaled drug for treating bronchial asthma.
• Therapeutic Function: Bronchodilator

Technology Process of Pirbuterol

There total 1 articles about Pirbuterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ pirbuterol (38677-81-5,146621-66-1,146621-69-4)

Guidance literature:

Refernces

• 1、 -. "Antiinflammatory salts of piroxicam". . . Retrieved 2008/06/13.
• 2、 -. "2-HYDROXYMETHYL-3-HYDROXY-6-(1-HYDROXY-2-AMINOETHYL)PYRIDINES". . . Retrieved 2014/02/08.