2,2,3,3-TETRAFLUORO-1,4-BUTANEDIOL

Base Information

• Chemical Name: 2,2,3,3-TETRAFLUORO-1,4-BUTANEDIOL
• CAS No.: 425-61-6
• Molecular Formula: C4H6F4O2
• Molecular Weight: 162.084
• Hs Code.: 2905590090
• Mol file: 425-61-6.mol

Synonyms:2,2,3,3-Tetrafluoro-1,4-butanediol;2,2,3,3-Tetrafluorobutanediol;NSC 95113;Tetrafluoro-1,4-butanediol;

Chemical Property of 2,2,3,3-TETRAFLUORO-1,4-BUTANEDIOL

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 0.000235mmHg at 25°C
• Melting Point: 77-82 °C (lit.)
• Refractive Index: 1.354
• Boiling Point: 289.9 °C at 760 mmHg
• PKA: 12.83±0.10(Predicted)
• Flash Point: 129.1 °C
• PSA: 40.46000
• Density: 1.454 g/cm³
• LogP: 0.24160
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility.: Soluble in water.

Purity/Quality:

98% ^*data from raw suppliers

2,2,3,3-Tetrafluoro-1,4-butanediol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Uses: 2,2,3,3-Tetrafluoro-1,4-butanediol is a reactant used for the enzymic synthesis of silicone fluorinated aliphatic polyester amides.

Technology Process of 2,2,3,3-TETRAFLUORO-1,4-BUTANEDIOL

There total 6 articles about 2,2,3,3-TETRAFLUORO-1,4-BUTANEDIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.8%

tetrafluorosuccinyl chloride (356-15-0) → 2,2,3,3-tetrafluorobutane-1,4-diol (425-61-6)

Guidance literature:

tetrafluorosuccinyl chloride; With ethanol; at 20 - 30 ℃; for 1h;

With sodium tetrahydroborate; ethanol; water; potassium hydroxide; at 10 - 20 ℃; for 0.5h; pH=Ca. 9;

Reference yield: 53.0%

perfluorosuccinic difluoride (679-13-0) → 2,2,3,3-tetrafluorobutane-1,4-diol (425-61-6)

Guidance literature:

perfluorosuccinic difluoride; With sodium tetrahydroborate; In isopropyl alcohol; at 5 - 80 ℃; for 3h;

With sulfuric acid; In isopropyl alcohol; at 35 ℃; for 1h;

Reference yield:

diethyl tetrafluorosuccinate (377-71-9) → 2,2,3,3-tetrafluorobutane-1,4-diol (425-61-6)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01122a049

upstream raw materials:

diethyl tetrafluorosuccinate

dimethyl tetrafluorosuccinate

2,2,3,3-tetrafluorobutane-1,4-diol diacetate

perfluorosuccinic difluoride

Refernces

• 1、 -. "FUNCTIONAL, PARTIALLY-FLUORINATED SILANES". Paragraph 0069. . Retrieved 2020/05/06.
• 2、 -. "Process for hydroxyalkylation of fluorinated alcohols". . . Retrieved 2008/06/13.