ERYTHROSIN B

Base Information

• Chemical Name: ERYTHROSIN B
• CAS No.: 15905-32-5
• Deprecated CAS: 10557-31-0,30495-83-1,875516-06-6,518-39-8,66771-70-8,19052-68-7,748740-60-5,76823-15-9,83412-54-8,2209062-14-4,19052-68-7,30495-83-1,518-39-8,66771-70-8,748740-60-5,76823-15-9,83412-54-8
• Molecular Formula: C20H8 I4 O5
• Molecular Weight: 835.899
• Hs Code.: 29329990
• European Community (EC) Number: 240-474-8,240-046-0
• NSC Number: 328781
• UNII: 1A878FZQ9B
• DSSTox Substance ID: DTXSID7044843
• Nikkaji Number: J25.137B
• Wikipedia: Erythrosine
• Wikidata: Q420101
• NCI Thesaurus Code: C87418
• RXCUI: 4061
• Metabolomics Workbench ID: 123329
• ChEMBL ID: CHEMBL1332616
• Mol file: 15905-32-5.mol

Synonyms:Fluorescein,2',4',5',7'-tetraiodo- (8CI); 2',4',5',7'-Tetraiodofluorescein;3',6'-Dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one;C.I. 45430:2; C.I. Solvent Red 140; Erythrosin J; Erythrosine J; Erythrosineacid; Iodeosin; NSC 328781; Solvent Red 140; Tetraiodofluorescein

Chemical Property of ERYTHROSIN B

Chemical Property:

• Appearance/Colour: powder
• Melting Point: 303 °C (dec.)(lit.)
• Boiling Point: 628.3 °C at 760 mmHg
• PKA: 7.21±0.20(Predicted)
• Flash Point: 333.8 °C
• PSA: 75.99000
• Density: 2.93 g/cm³
• LogP: 6.08420
• Storage Temp.: Store at RT.
• Solubility.: spirit: soluble
• Water Solubility.: Soluble in water, spirit, methanol, methyl cellosolve and ethanol.
• XLogP3: 6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 835.6551
• Heavy Atom Count: 29
• Complexity: 645

Purity/Quality:

99% ^*data from raw suppliers

Erythrosin B ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)I)O)I)I)O)I
• Uses: Indicator in analytical chemistry. Erythrosin B is used as a red coloring in some foods such as cherries and fish. It is used as printing ink, dental plaque disclosing agent and biological stain. It finds application as a radiopaque medium and sensitizer for orthochromatic photographic films. It is utilized as a cake-decorating gel. In addition to this, it is used in sweets such as candies and popsicles. Erythrosin B has been used as a dye in fluorescence lifetime imaging.

Technology Process of ERYTHROSIN B

There total 5 articles about ERYTHROSIN B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

fluorescein (2321-07-5,126605-73-0) → 2',4',5'-triiodofluorescein (56254-06-9) + erythrosine B (15905-32-5,767625-50-3)

Guidance literature:

With Oxone; sodium iodide; at 200 ℃; for 12h;

Reference yield:

fluorescein (2321-07-5,126605-73-0) → erythrosine B (15905-32-5,767625-50-3)

Guidance literature:

With iodine; Behandeln mit Eisessig;

Reference yield:

ethanol (64-17-5) + fluorescein (2321-07-5,126605-73-0) → erythrosine B (15905-32-5,767625-50-3)

Guidance literature:

With pyridine; iodine; silver nitrate;

upstream raw materials:

ethanol

fluorescein

Downstream raw materials:

2',4',5',7'-tetraiodofluorescein disodium salt

Refernces

• 1、 -. "Nucleic acid size detection method". . . Retrieved 2012/05/04.
• 2、 -. "Substractive single label comparative hybridization". . . Retrieved 2009/04/24.