1,2,10-Trimethoxy-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-9-ol

Base Information

• Chemical Name: 1,2,10-Trimethoxy-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-9-ol
• CAS No.: 128-76-7
• Molecular Formula: C₁₉H₂₁NO₄
• Molecular Weight: 327.38
• NSC Number: 106610
• Wikidata: Q104394460
• Metabolomics Workbench ID: 44265
• ChEMBL ID: CHEMBL4090368
• Mol file: 128-76-7.mol

Synonyms:Laurotetanin;Litsoeine;1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-9-ol;128-76-7;(+)-Laurotetanine;Litsoene;NSC 106610;Compound NP-019525;SCHEMBL905125;CHEMBL4090368;CHEBI:182323;NSC106610;AKOS040738198;9-Hydroxy-1,2,10-trimethoxynoraporphine;6a.alpha.-Noraporphin-9-ol,2,10-trimethoxy-;6aalpha 1,2,10-Trimethoxy--Noraporphin-9-ol;4H-Dibenzo[de, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-, (S)-;NCGC00385613-01!1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-9-ol;4,15,16-trimethoxy-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,13,15-hexaen-5-ol

Chemical Property of 1,2,10-Trimethoxy-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-9-ol

Chemical Property:

• Vapor Pressure: 1.3E-11mmHg at 25°C
• Melting Point: 125°C
• Refractive Index: 1.5000 (estimate)
• Boiling Point: 524.4°Cat760mmHg
• Flash Point: 270.9°C
• PSA: 59.95000
• Density: 1.239g/cm³
• LogP: 3.15670
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 327.14705815
• Heavy Atom Count: 24
• Complexity: 447

Purity/Quality:

98%min ^*data from raw suppliers

LAUROTETANINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C2=C3C(CC4=CC(=C(C=C42)OC)O)NCCC3=C1)OC
• Description: The noraporphine alkaloid was first isolated by Greshoff from Litsea chrysocorna and subsequently from other species of Lauraceae including L. citrata and L. cubeba. When freshly crystallized from Me2 CO it yields colourless crystals but these become yellow in air. The alkaloid behaves as a phenolic base giving salts with mineral acids which all contain H20 of crystallization. The picrate monohydrate has m.p. 1480 C, the dibenzoyl derivative, m.p. 169-1700 C and the phenylthiocarbamide, m.p. 211-2°C. Three methoxyl groups, an imino group and a phenolic hydroxyl group are present, the latter giving the O-methyl ether which is an amorphous powder but yields a crystalline hydrochloride, m.p. 245°C; an oxalate, m.p. 233°C and the thiocarbamide, m.p. 154-5°C. The Nmethyl derivative (q.v.) is found naturally in Peurnus boldus and the O,Ndimethyl derivative is glaucine. The structure has been determined from chemical degradation and synthesis.

Technology Process of 1,2,10-Trimethoxy-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-9-ol

There total 1 articles about 1,2,10-Trimethoxy-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-9-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (+)-laurotetanine (128-76-7,65877-55-6,84172-45-2)

Guidance literature:

Darstellung aus der Rinde von Tetranthera citrata;