2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole

Base Information

• Chemical Name: 2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole
• CAS No.: 67730-11-4
• Molecular Formula: C11H10 N4
• Molecular Weight: 198.25
• European Community (EC) Number: 689-082-2
• UNII: RXM718XV6O
• DSSTox Substance ID: DTXSID5020657
• Nikkaji Number: J22.202J
• Wikidata: Q27155880
• Metabolomics Workbench ID: 44037
• Mol file: 67730-11-4.mol

Synonyms:2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole;Glu P-1;Glu-P-1

Chemical Property of 2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole

Chemical Property:

• Melting Point: >300oC
• Refractive Index: 1.4260 (estimate)
• Boiling Point: 363.7°Cat760mmHg
• Flash Point: 173.8°C
• PSA: 65.44000
• Density: 1.41g/cm³
• LogP: 3.09200
• Storage Temp.: Store at room temperature
• Sensitive.: Light Sensitive
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 198.090546336
• Heavy Atom Count: 15
• Complexity: 245

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-6-methyldipyrido[1,2-a:3'',2''-d]imidazoleHydrochlorideHydrate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CN2C1=NC3=C2N=C(C=C3)N
• Uses: A mutagenic component isolated from L-glutamic acid pyrolysate

Technology Process of 2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole

There total 2 articles about 2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

→ 2-(aminopropyl)amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole + 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (67730-11-4)

Guidance literature:

Reference yield:

→ 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (67730-11-4)

Guidance literature:

3-Amino-8-methylimidazo<1,2-a>pyridin,2-Chloracrylonitril(AlCl3);

DOI:10.1248/cpb.26.2924

Reference yield: 92.0%

2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (67730-11-4) + O6-benzyl-8-bromo-3′,5′-O-bis(tert-butyldimethylsilyl)-N2-dimethoxytrityl-2′-deoxyguanosine (479408-23-6) → 6-benzyloxy-N2-[bis-(4-methoxy-phenyl)-phenyl-methyl]-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-N8-(6-methyl-dipyrido[1,2-a;3',2'-d]imidazol-2-yl)-9H-purine-2,8-diamine (896719-52-1)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 100 ℃;

DOI:10.1021/tx050296s

Downstream raw materials:

2-nitro-6-methyldipyridi<1,2-a:3',2'-d>imidazole

6-benzyloxy-N²-[bis-(4-methoxy-phenyl)-phenyl-methyl]-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-N⁸-(6-methyl-dipyrido[1,2-a;3',2'-d]imidazol-2-yl)-9H-purine-2,8-diamine

6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-N⁸-(6-methyl-dipyrido[1,2-a;3',2'-d]imidazol-2-yl)-9H-purine-2,8-diamine

2-phenyl(N,N,O)azoxy-6-methyldipyridi<1,2-a:3',2'-d>imidazole

Refernces

• 1、 -. "Porphyrin derivatives". . . Retrieved 2008/06/13.