DFSP

Base Information

• Chemical Name: DFSP
• CAS No.: 2515-62-0
• Molecular Formula: C23H20 N2
• Molecular Weight: 324.425
• Hs Code.: 2933199090
• Mol file: 2515-62-0.mol

Synonyms:2-Pyrazoline,1,5-diphenyl-3-styryl- (6CI,7CI,8CI); 1,5-Diphenyl-3-(2-styryl)-D2-pyrazoline; 1,5-Diphenyl-3-(b-styryl)-2-pyrazoline;1,5-Diphenyl-3-styryl-2-pyrazoline; 1,5-Diphenyl-3-styryl-D2-pyrazoline;1,5-Diphenyl-3-styrylpyrazoline; 1,5-Diphenyl-b-styrylpyrazoline; DFSP; DSP; DSP (scintillator);Pyrazoline 1

Chemical Property of DFSP

Chemical Property:

• PSA: 15.60000
• LogP: 5.20800

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DFSP

There total 15 articles about DFSP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

phenylhydrazine (100-63-0) + 1,5-diphenyl-1,4-pentadiene-3-one (538-58-9) → 1,5-Diphenyl-3-styryl-2-pyrazoline (2515-62-0,325150-61-6)

Guidance literature:

With cellulose sulfonic acid; In ethanol; at 60 ℃; for 2h; Reagent/catalyst; Solvent; Temperature; Green chemistry;

DOI:10.1039/c5ra19773b

Reference yield: 96.0%

dibenzylideneacetone (35225-79-7) + phenylhydrazine (100-63-0) → 1,5-diphenyl-3-[(E)-2-phenylethenyl]-4,5-dihydro-1H-pyrazoline (2515-62-0,325150-61-6)

Guidance literature:

With potassium hydrogensulfate; silica gel; for 0.075h; microwave irradiation;

DOI:10.1080/00397910600764766

Reference yield: 89.0%

tris-(dibenzylideneacetone)dipalladium(0) (52409-22-0,51364-51-3) + phenylhydrazine (100-63-0) → 1,5-Diphenyl-3-styryl-2-pyrazoline (2515-62-0,325150-61-6)

Guidance literature:

In water; at 100 ℃; for 0.0833333h; Solvent; Microwave irradiation;

DOI:10.1039/c8ra04550j

upstream raw materials:

phenylhydrazine

1,5-diphenyl-1,4-pentadiene-3-one

1-Phenylbut-1-en-3-one

benzaldehyde

Downstream raw materials:

1,2,5-triphenyl-1,2,3,5,6,7-hexahydro-pyrazolo[1,5-a]pyridine-6,7-dicarboxylic acid anhydride

1,5-diphenyl-3-styryl-1H-pyrazole

2,6-Diphenyl-4-{4-[5-phenyl-3-((E)-styryl)-4,5-dihydro-pyrazol-1-yl]-phenyl}-pyridine

1,5-diphenyl-3-[(E)-2-phenylethenyl]-1H-pyrazole

Refernces

• 1、 El Kerdawy, Ahmed M.,El-Ansary, Dina Y.,George, Riham F.,Kandeel, Manal. "Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking". . . Retrieved 2020/03/31.
• 2、 Venkateswarlu, Vunnam,Kour, Jaspreet,Kumar, K. A. Aravinda,Verma, Praveen Kumar,Reddy, G. Lakshma,Hussain, Yaseen,Tabassum, Aliya,Balgotra, Shilpi,Gupta, Sorav,Hudwekar, Abhinandan D.,Vishwakarma, Ram A.,Sawant, Sanghapal D.. "Direct N-heterocyclization of hydrazines to access styrylated pyrazoles: synthesis of 1,3,5-trisubstituted pyrazoles and dihydropyrazoles". . p. 26523 - 26527. Retrieved 2018/08/07.