Technology Process of 5-Bromo-2-methylbenzenethiol
There total 5 articles about 5-Bromo-2-methylbenzenethiol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
S-5-bromo-2-methylphenyl O-ethylcarbonodithioate;
With
potassium hydroxide;
In
ethanol;
for 5h;
Reflux;
With
hydrogenchloride;
In
ethanol; water;
DOI:10.1039/c3ob40250a
- Guidance literature:
-
5-bromo-2-methylaniline;
With
hydrogenchloride; sodium nitrite;
In
water;
at -10 - -5 ℃;
for 0.666667h;
With
potassium ethyl xanthogenate;
In
water;
at 65 ℃;
for 0.833333h;
With
potassium hydroxide;
In
ethanol;
for 18h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogenchloride; sodium nitrite / water / 2.5 h / 0 °C / Reflux
1.2: 1 h
2.1: potassium hydroxide / ethanol / 5 h / Reflux
With
hydrogenchloride; potassium hydroxide; sodium nitrite;
In
ethanol; water;
DOI:10.1039/c3ob40250a
