Ethyl DL-methionate hydrochloride

Base Information

• Chemical Name: Ethyl DL-methionate hydrochloride
• CAS No.: 6297-53-6
• Molecular Formula: C7H15 N O2 S . Cl H
• Molecular Weight: 213.729
• Hs Code.: 2930909090
• European Community (EC) Number: 228-571-3
• Mol file: 6297-53-6.mol

Synonyms:Ethyl DL-methionate hydrochloride;Ethyl DL-methionate HCl;EINECS 228-571-3;NSC 46033;ethyl 2-amino-4-methylsulfanylbutanoate;chloride

Chemical Property of Ethyl DL-methionate hydrochloride

Chemical Property:

• Vapor Pressure: 0.0142mmHg at 25°C
• Melting Point: 72-75°C
• Boiling Point: 257.9ºC at 760 mmHg
• Flash Point: 109.8ºC
• PSA: 77.62000
• LogP: 2.13220
• Storage Temp.: Store at 0-5°C
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 212.0512026
• Heavy Atom Count: 12
• Complexity: 119

Purity/Quality:

99% ^*data from raw suppliers

Dl-MethionineEthylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(CCSC)N.[Cl-]

Technology Process of Ethyl DL-methionate hydrochloride

There total 2 articles about Ethyl DL-methionate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

→ methionine ethyl ester hydrochloride (6297-53-6)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃;

Reference yield:

ethanol (64-17-5) + DL-methionine (59-51-8,26062-47-5,58576-49-1) → methionine ethyl ester hydrochloride (6297-53-6)

Guidance literature:

With hydrogenchloride;

Reference yield: 70.0%

isatoic anhydride (118-48-9) + methionine ethyl ester hydrochloride (6297-53-6) → 2-(RS)-(2-aminobenzoylamino)-4-methylsulfanylbutyric acid ethyl ester (296282-27-4)

Guidance literature:

With triethylamine; In ethyl acetate; for 2h; Heating;

DOI:10.1016/S0014-827X(00)00043-4

upstream raw materials:

ethanol

DL-methionine

Downstream raw materials:

(+/-)-ethyl 2-isocyanato-4-methylthiobutyrate

2-Isothiocyanato-4-methylsulfanyl-butyric acid ethyl ester

2-[1-(Hydroxy-diphenyl-methyl)-3-methylsulfanyl-propylamino]-cyclopent-1-enecarbonitrile

2-[(3,5-Dimethyl-1-phenyl-1H-pyrazole-4-carbonyl)-amino]-4-methylsulfanyl-butyric acid ethyl ester

Refernces

• 1、 Lassiani, Lucia,Pavan, Michela V.,Berti, Federico,Kokotos, George,Markidis, Theodoros,Mennuni, Laura,Makovec, Francesco,Varnavas, Antonio. "Anthranilic acid based CCK1 receptor antagonists: Blocking the receptor with the same 'words' of the endogenous ligand". experimental part. p. 2336 - 2350. Retrieved 2009/09/05.