4-(morpholin-4-yl-phenoxy-phosphoryl)morpholine

Base Information

• Chemical Name: 4-(morpholin-4-yl-phenoxy-phosphoryl)morpholine
• CAS No.: 4881-17-8
• Molecular Formula: C₁₄H₂₁N₂O₄P
• Molecular Weight: 312.305
• Mol file: 4881-17-8.mol

Synonyms:Phosphinicacid, di-4-morpholinyl-, phenyl ester (9CI); Phosphinic acid, dimorpholino-,phenyl ester (6CI,7CI,8CI); NSC 41249

Chemical Property of 4-(morpholin-4-yl-phenoxy-phosphoryl)morpholine

Chemical Property:

• Vapor Pressure: 5.99E-08mmHg at 25°C
• Boiling Point: 440.2°Cat760mmHg
• Flash Point: 220°C
• PSA: 61.05000
• Density: 1.29g/cm³
• LogP: 1.71370

Purity/Quality:

99% ^*data from raw suppliers

DIMORPHOLINOPHOSPHINIC ACID PHENYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(morpholin-4-yl-phenoxy-phosphoryl)morpholine

There total 3 articles about 4-(morpholin-4-yl-phenoxy-phosphoryl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) → di-morpholin-4-yl-phosphinic acid phenyl ester (4881-17-8)

Guidance literature:

With pyridine; trichlorophosphate; phenol;

DOI:10.1021/ja01258a029

Reference yield:

morpholine (110-91-8,99108-56-2) + O-phenyl phosphorodichloridate (770-12-7) → di-morpholin-4-yl-phosphinic acid phenyl ester (4881-17-8)

Guidance literature:

DOI:10.1021/ja01258a029 DOI:10.1039/jr9580001963

Reference yield:

→ di-morpholin-4-yl-phosphinic acid phenyl ester (4881-17-8)

Guidance literature:

from the appropr. phenyl phosphordichloridate ,morpholine;

upstream raw materials:

morpholine

O-phenyl phosphorodichloridate

Downstream raw materials:

morpholin-4-yl-phosphonic acid monophenyl ester