Butanedioic acid, hydroxy-, 1-ethyl ester

Base Information

• Chemical Name: Butanedioic acid, hydroxy-, 1-ethyl ester
• CAS No.: 71901-42-3
• Molecular Formula: C6H10O5
• Molecular Weight: 162.142
• Mol file: 71901-42-3.mol

Synonyms:malic acid monoethyl ester;2-Hydroxy-succinic acid 1-ethyl ester;Monoaethyl-DL-malat;ethyl malate;Aepfelsaeure-monoaethylester;

Chemical Property of Butanedioic acid, hydroxy-, 1-ethyl ester

Chemical Property:

• PSA: 83.83000
• LogP: -0.61490

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Butanedioic acid, hydroxy-, 1-ethyl ester

There total 2 articles about Butanedioic acid, hydroxy-, 1-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

ethanol (64-17-5) + malic acid (617-48-1,78644-42-5) → 4-ethoxy-3-hydroxy-4-oxobutanoic acid (71901-42-3)

Guidance literature:

With boric acid; at 20 ℃; for 18h;

DOI:10.1021/ol036123g

Reference yield:

→ 4-ethoxy-3-hydroxy-4-oxobutanoic acid (71901-42-3)

Guidance literature:

With 1,4-dioxane; selenium(IV) oxide;

DOI:10.1039/jr9350000901

Reference yield:

4-ethoxy-3-hydroxy-4-oxobutanoic acid (71901-42-3) → sodium malate (138-09-0,676-46-0,3105-51-9,20786-58-7,22798-10-3,40520-93-2,51209-20-2,57467-17-1,58214-38-3,63441-17-8,68303-40-2,97251-45-1,129283-54-1)

Guidance literature:

With water; sodium hydroxide; for 0.00555556h; pH=12.9;

upstream raw materials:

ethanol

malic acid

Downstream raw materials:

sodium malate

Refernces