Heptadecanedioic acid, monomethyl ester

Base Information

• Chemical Name: Heptadecanedioic acid, monomethyl ester
• CAS No.: 72849-42-4
• Molecular Formula: C18H34O4
• Molecular Weight: 313.45200
• Mol file: 72849-42-4.mol

Synonyms:Heptadecan-1,17-disaeuremonomethylester;Heptadecanedioic acid,monomethyl ester;

Chemical Property of Heptadecanedioic acid, monomethyl ester

Chemical Property:

• PSA: 66.43000
• LogP: 3.76080

Purity/Quality:

98.5% ^*data from raw suppliers

17-Methoxy-17-oxoheptadecanoicacid 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Heptadecanedioic acid, monomethyl ester

There total 10 articles about Heptadecanedioic acid, monomethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.7%

dimethyl heptadecane-1,17-dioate (19102-92-2) → heptadecanedioic acid monomethyl ester (72849-42-4)

Guidance literature:

With methanol; barium(II) hydroxide; at 10 - 25 ℃; for 34h; Inert atmosphere;

Reference yield:

heptadecanedioic acid (2424-90-0) → heptadecanedioic acid monomethyl ester (72849-42-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / 2 h / Reflux

2: barium(II) hydroxide / tetrahydrofuran; methanol / 18 h / 20 °C

With sulfuric acid; barium(II) hydroxide; In tetrahydrofuran; methanol;

DOI:10.1002/ejoc.201101563

Reference yield:

1,13-bis(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)tridecane (1374572-51-6) → heptadecanedioic acid monomethyl ester (72849-42-4)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride; water / Reflux

2: sulfuric acid / 2 h / Reflux

3: barium(II) hydroxide / tetrahydrofuran; methanol / 18 h / 20 °C

With hydrogenchloride; sulfuric acid; water; barium(II) hydroxide; In tetrahydrofuran; methanol;

DOI:10.1002/ejoc.201101563

upstream raw materials:

methyl 17-aminoheptadecanoate

1,18-octadecanedioic acid monomethyl ester

dimethyl 1,18-octadecanedioate

17-Carbamoyl-heptadecanoic acid methyl ester

Downstream raw materials:

17-hydroxy-heptadecanoic acid methyl ester

17-hydroxy-heptadecanoic acid

heptadecanedioic acid

Refernces

• 1、 Haulotte, Eveline,Laurent, Pascal,Braekman, Jean-Claude. "Biosynthesis of defensive coccinellidae alkaloids: Incorporation of fatty acids in adaline, coccinelline, and harmonine". . p. 1907 - 1912. Retrieved 2012/05/31.