Phosphorous acid, 1-methylethyl diphenyl ester

Base Information

• Chemical Name: Phosphorous acid, 1-methylethyl diphenyl ester
• CAS No.: 7330-17-8
• Molecular Formula: C15H17O3P
• Molecular Weight: 276.272
• Mol file: 7330-17-8.mol

Synonyms:

Chemical Property of Phosphorous acid, 1-methylethyl diphenyl ester

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphorous acid, 1-methylethyl diphenyl ester

There total 6 articles about Phosphorous acid, 1-methylethyl diphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

O,O-diphenyl N-dimethylamidophosphite (19620-78-1) + isopropyl alcohol (67-63-0,8013-70-5) → isopropyl diphenyl phosphite (7330-17-8)

Guidance literature:

With 1H-tetrazole; In 1,2-dimethoxyethane; at 20 ℃; for 7h;

DOI:10.1039/b616450a

Reference yield: 30.0%

isopropyl alcohol (67-63-0,8013-70-5) + phenol (108-95-2,27073-41-2) → isopropyl diphenyl phosphite (7330-17-8)

Guidance literature:

With triethylamine; phosphorus trichloride; In diethyl ether; at 20 ℃;

DOI:10.1039/b616450a

Reference yield:

diphenyl-N,N-diethylphosphoramidite (14747-96-7) + isopropyl alcohol (67-63-0,8013-70-5) → isopropyl diphenyl phosphite (7330-17-8)

Guidance literature:

With 1H-tetrazole; In 1,2-dimethoxyethane; at 20 ℃; for 6h; Yield given;

DOI:10.1039/c39910000667

upstream raw materials:

Diphenyl phosphorochloridite

isopropyl alcohol

diphenyl-N,N-diethylphosphoramidite

O,O-diphenyl N-dimethylamidophosphite

Downstream raw materials:

((3aR,5S,5aR,8aS,8bR)-2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-ylmethyl)-phosphonic acid diphenyl ester

methyl 2-O-benzyl-6-deoxy-6-diphenoxyphosphinyl-3,4-O-isopropylidene-β-D-galactoside

[(3aR,4S,6S,7R,7aS)-6-Methoxy-7-(4-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethyl]-phosphonic acid diphenyl ester

Refernces

• 1、 Wang, Meng Fang,Crilley, Martine M. L.,Golding, Bernard T.,McInally, Tom,Robinson, David H.,Tinker, Alan. "Synthesis of Phosphonates: a Modified Arbuzov Procedure". . p. 667 - 668. Retrieved 2007/10/02.