(2,2-diphenylacetyl) 2,2-diphenylacetate

Base Information

• Chemical Name: (2,2-diphenylacetyl) 2,2-diphenylacetate
• CAS No.: 1760-46-9
• Molecular Formula: C28H22 O3
• Molecular Weight: 406.481
• Hs Code.: 2916399090
• Mol file: 1760-46-9.mol

Synonyms:Aceticacid, diphenyl-, anhydride (6CI,7CI,8CI); Benzeneacetic acid, a-phenyl-, anhydride (9CI);Diphenylacetic acid anhydride; Diphenylacetic anhydride; NSC 402007

Chemical Property of (2,2-diphenylacetyl) 2,2-diphenylacetate

Chemical Property:

• Vapor Pressure: 1.97E-12mmHg at 25°C
• Melting Point: 96.0 to 100.0 °C
• Refractive Index: 1.5460 (estimate)
• Boiling Point: 556.7°Cat760mmHg
• Flash Point: 268.4°C
• PSA: 43.37000
• Density: 1.18g/cm³
• LogP: 5.72040
• Solubility.: soluble in Toluene

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diphenylacetic Anhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2,2-diphenylacetyl) 2,2-diphenylacetate

There total 27 articles about (2,2-diphenylacetyl) 2,2-diphenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,2-diphenylacetic acid (117-34-0) + potassium diphenylacetate → diphenylacetic anhydride (1760-46-9)

Guidance literature:

2,2-diphenylacetic acid; With trichloroisocyanuric acid; triphenylphosphine; In dichloromethane; at 0 - 20 ℃;

potassium diphenylacetate; In dichloromethane; at 20 ℃; for 1.33333h;

DOI:10.1515/chempap-2015-0042

Reference yield: 90.0%

2,2-diphenylacetic acid (117-34-0) → diphenylacetic anhydride (1760-46-9)

Guidance literature:

With dicyclohexyl-carbodiimide; In 1,4-dioxane; diethyl ether; 3 h, r.t., 1 h, 0 deg C;

Reference yield:

dimethylmalonic acid diphenylacetic acid-anhydride → dimethylketene (598-26-5) + diphenylacetic anhydride (1760-46-9) + methylammonium carbonate (15719-64-9,15719-76-3,97762-63-5)

Guidance literature:

beim Erhitzen unter vermindertem Druck;

upstream raw materials:

diphenylacetic acid chloride

2,2-diphenylacetic acid

acetic anhydride

malonic acid

Downstream raw materials:

N-[9-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-9H-purin-6-yl]-2,2-diphenyl-acetamide

Diphenylmethane

2,2-diphenylacetic acid

1,1,2,2-tetraphenylethylene

Refernces

• 1、 Briody,J.M. et al.. "-". . p. 885 - 889. Retrieved 1968.
• 2、 Qu, Shen,Greenhalgh, Mark D.,Smith, Andrew D.. "Isothiourea-Catalysed Regioselective Acylative Kinetic Resolution of Axially Chiral Biaryl Diols". supporting information. p. 2816 - 2823. Retrieved 2019/02/05.
• 3、 Nakata, Kenya,Sekiguchi, Akihiro,Shiina, Isamu. "A convenient method for the kinetic resolution of racemic 2-hydroxyalkanoates using diphenylacetic anhydride (DPHAA) and a chiral acyl-transfer catalyst". scheme or table. p. 1610 - 1619. Retrieved 2012/01/03.