2-Bromo-6-ethylaniline

Base Information

• Chemical Name: 2-Bromo-6-ethylaniline
• CAS No.: 73621-39-3
• Molecular Formula: C8H10BrN
• Molecular Weight: 200.078
• DSSTox Substance ID: DTXSID20479653
• Wikidata: Q82313797
• Mol file: 73621-39-3.mol

Synonyms:2-bromo-6-ethylaniline;73621-39-3;Benzenamine, 2-bromo-6-ethyl-;SCHEMBL11137835;DTXSID20479653

Chemical Property of 2-Bromo-6-ethylaniline

Chemical Property:

• PSA: 26.02000
• LogP: 3.17490
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 198.99966
• Heavy Atom Count: 10
• Complexity: 105

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=C(C(=CC=C1)Br)N

Technology Process of 2-Bromo-6-ethylaniline

There total 4 articles about 2-Bromo-6-ethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

ortho-ethylaniline (578-54-1) → 2-bromo-6-ethylaniline (73621-39-3)

Guidance literature:

With dihydrogen peroxide; copper diacetate; potassium bromide; In water; at 20 ℃; for 2h;

Reference yield:

1-bromo-3-ethyl-2-nitrobenzene (702642-07-7) → 2-bromo-6-ethylaniline (73621-39-3)

Guidance literature:

With hydrogenchloride; ethanol; tin(ll) chloride;

Reference yield:

3-ethyl-2-nitrobenzeneamine (702642-03-3) → 2-bromo-6-ethylaniline (73621-39-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Diazotization_.Behandlung der Diazoniumsalz-Loesung mit CuBr in wss. HBr in der Waerme

2: tin (II)-chloride; hydrogen chloride; ethanol

With hydrogenchloride; ethanol; tin(ll) chloride;

upstream raw materials:

1-bromo-3-ethyl-2-nitrobenzene

3-ethyl-2-nitrobenzeneamine

1-ethyl-2,3-dinitrobenzene

ortho-ethylaniline

Refernces