7-oxabicyclo[4.1.0]hept-3-ylmethyl acetate

Base Information

• Chemical Name: 7-oxabicyclo[4.1.0]hept-3-ylmethyl acetate
• CAS No.: 75228-31-8
• Molecular Formula: C₉H₁₄O₃
• Molecular Weight: 170.208
• Mol file: 75228-31-8.mol

Synonyms:

Chemical Property of 7-oxabicyclo[4.1.0]hept-3-ylmethyl acetate

Chemical Property:

• Vapor Pressure: 0.0718mmHg at 25°C
• Boiling Point: 228.9°Cat760mmHg
• Flash Point: 96.9°C
• Density: 1.106g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-oxabicyclo[4.1.0]hept-3-ylmethyl acetate

There total 6 articles about 7-oxabicyclo[4.1.0]hept-3-ylmethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cyclohex-3-enylmethyl acetate (117266-97-4,20144-30-3) → 1-methylcarbonyloxymethyl-3-cyclohexene oxide (81370-41-4,81370-42-5,75228-31-8)

Guidance literature:

With [2-percarboxyethyl] functionalized silica; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/jo300533b

Reference yield:

cyclohex-3-enylmethyl acetate (117266-97-4,20144-30-3) → Acetic acid (1S,3S,6R)-1-(7-oxa-bicyclo[4.1.0]hept-3-yl)methyl ester (75228-31-8,81370-41-4,81370-42-5)

Guidance literature:

With tert.-butylhydroperoxide; disodium hydrogenphosphate; hexacarbonyl molybdenum; In 1,2-dichloro-ethane; for 2h; Yield given; Heating;

DOI:10.1021/jo00192a039

Reference yield:

cyclohex-3-enylmethanol (72581-32-9,1679-51-2) → Acetic acid (1S,3S,6R)-1-(7-oxa-bicyclo[4.1.0]hept-3-yl)methyl ester (75228-31-8,81370-41-4,81370-42-5)

Guidance literature:

Multi-step reaction with 2 steps

1: tert-butyl hydroperoxide (TBHP) / Mo(CO)6/Na₂HPO₄ / 1,2-dichloro-ethane / 2 h / Heating

2: pyridine

With tert.-butylhydroperoxide; disodium hydrogenphosphate; hexacarbonyl molybdenum; In pyridine; 1,2-dichloro-ethane;

DOI:10.1021/jo00192a039

upstream raw materials:

Perbenzoic acid

cyclohex-3-enylmethyl acetate

cyclohex-3-enylmethanol

(1R*,3R*,6S*)-7-oxabicyclo[4.1.0]hept-3-ylmethanol

Refernces

• 1、 Mello, Rossella,Alcalde-Aragones, Ana,Olmos, Andrea,Gonzalez-Nunez, Maria Elena,Asensio, Gregorio. "Epoxidation of olefins with a silica-supported peracid in supercritical carbon dioxide under flow conditions". experimental part. p. 4706 - 4710. Retrieved 2012/07/28.
• 2、 Majetich, George,Hicks, Rodgers,Sun, Guang-Ri,McGill, Patrick. "Carbodiimide-Promoted Olefin Epoxidation with Aqueous Hydrogen Peroxide". . p. 2564 - 2573. Retrieved 2007/10/03.