Cnp-maltotrioside

Base Information

• Chemical Name: Cnp-maltotrioside
• CAS No.: 118291-90-0
• Molecular Formula: C₂₄H₃₄ClNO₁₈
• Molecular Weight: 659.983
• Hs Code.: 29400090
• DSSTox Substance ID: DTXSID20922654
• Wikidata: Q72455981
• Mol file: 118291-90-0.mol

Synonyms:2-chloro-4-nitrophenyl-alpha-maltotrioside;2-chloro-4-nitrophenylmaltotrioside;CNP-G3;CNP-maltotrioside

Chemical Property of Cnp-maltotrioside

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 973°Cat760mmHg
• PKA: 12.44±0.70(Predicted)
• Flash Point: 542.2°C
• PSA: 303.50000
• Density: 1.84g/cm³
• LogP: -4.40150
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Water (Slightly)
• XLogP3: -4
• Hydrogen Bond Donor Count: 11
• Hydrogen Bond Acceptor Count: 18
• Rotatable Bond Count: 8
• Exact Mass: 659.1464409
• Heavy Atom Count: 44
• Complexity: 965

Purity/Quality:

98%, ^*data from raw suppliers

2-Chloro-4-nitrophenyl a-D-maltotrioside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C=C1[N+](=O)[O-])Cl)C2(C(C(C(C(O2)CO)O)O)OC3C(C(C(C(O3)CO)O)O)O)OC4C(C(C(C(O4)CO)O)O)O
• Isomeric SMILES: C1=CC(=C(C=C1[N+](=O)[O-])Cl)[C@]2([C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O
• Uses: 2-Chloro-4-nitrophenyl-α-D-maltotrioside has been used as a substrate in assays to determine the enzymatic activity of α-amylase.

Technology Process of Cnp-maltotrioside

There total 12 articles about Cnp-maltotrioside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.3%

2-chloro-4-nitrophenyl β-maltoheptoside (90826-64-5) → 2-chloro-4-nitrophenyl-β-maltopentoside (99304-80-0) + o-chloro-p-nitrophenyl β-maltotetraoside (145072-72-6) + (2R,3R,4S,5S,6R)-2-{(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6S)-6-(2-Chloro-4-nitro-phenoxy)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy]-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy}-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol (118291-90-0,157381-11-8,165522-16-7) + 2-chloro-4-nitrophenyl O-(α-D-glucopyranosyl)-(1->4)-tetrakis-[O-α-D-glucopyranosyl-(1->4)]-β-D-glucopyranoside (198561-63-6)

Guidance literature:

With 2-hydroxyethanethiol; glycogen phosphorylase b; In phosphate buffer; at 30 ℃; for 5h; pH=6.8; Further Variations:; Temperatures; times; Product distribution; Enzymatic reaction;

DOI:10.1016/S0008-6215(98)00324-3

Reference yield:

C48H74ClNO38 (1512800-77-9) → C24H34ClNO18 (118291-90-0,157381-11-8,165522-16-7)

Guidance literature:

With limit dextrinase; calcium chloride; In aq. acetate buffer; at 45 ℃; pH=5.3; Temperature; Enzymatic reaction;

DOI:10.1016/j.ab.2013.12.004

Reference yield:

C44H54ClNO28 → (2R,3R,4S,5S,6R)-2-{(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6S)-6-(2-Chloro-4-nitro-phenoxy)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy]-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy}-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol (118291-90-0,157381-11-8,165522-16-7)

Guidance literature:

With sodium methylate; In methanol; for 24h; Ambient temperature; pH ca./= 8;

DOI:10.1016/S0008-6215(97)00187-0

upstream raw materials:

2-chloro-4-nitrophenyl β-maltoheptoside

2-chloro-4-nitrophenyl-β-maltopentoside

o-chloro-p-nitrophenyl β-maltotetraoside

2-chloro-4-nitrophenyl O-(α-D-glucopyranosyl)-(1->4)-tetrakis-[O-α-D-glucopyranosyl-(1->4)]-β-D-glucopyranoside

Downstream raw materials:

maltotriose

2-chloro-4-nitrophenol

β-D-glucose

4,6-O-benzylidene-2-chloro-4-nitrophenyl cellotrioside

Refernces

• 1、 B?jstrup, Marie,Christensen, Caspar Elo,Windahl, Michael Skovbo,Henriksen, Anette,Hindsgaul, Ole. "A chromogenic assay for limit dextrinase and pullulanase activity". . p. 45 - 51. Retrieved 2014/02/14.
• 2、 Farkas, Erzsebet,Janossy, Lorant,Harangi, Janos,Kandra, Lili,Liptak, Andras. "Synthesis of chromogenic substrates of α-amylases on a cyclodextrin basis". . p. 407 - 415. Retrieved 2007/10/03.