1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE

Base Information Edit

Chemical Name:1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE
CAS No.:76893-27-1
Molecular Formula:C10H18NO4S
Molecular Weight:248.323
Hs Code.:
Mol file:76893-27-1.mol

Synonyms:1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE;

Suppliers and Price of 1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Oxyl-2,2,5,5-tetramethyl-?3-(methanesulfonyloxymethyl)pyrroline
250mg
$ 2360.00

American Custom Chemicals Corporation
1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE 95.00%
5MG
$ 504.77

Total 3 raw suppliers

Chemical Property of 1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:80-83°C
PSA：54.99000
LogP:2.12600
Storage Temp.:-20°C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

1-Oxyl-2,2,5,5-tetramethyl-?3-(methanesulfonyloxymethyl)pyrroline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE

There total 6 articles about 1-OXYL-2,2,5,5-TETRAMETHYL-3-(METHANESULFONYLOXYMETHYL)PYRROLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 55738-75-5
(2,5-dihydro-2,2,5,5-tetramethyl-1-oxyl-1H-pyrrol-3-yl)methanol

: 124-63-0
methanesulfonyl chloride

: 76893-27-1
(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl methanesulfonate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 1.16667h;
DOI:10.1021/acs.orglett.9b04216

Reference yield:

: 826-36-8
2,2,6,6-Tetramethyl-4-piperidone

: 76893-27-1
(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl methanesulfonate

Guidance literature:: Multi-step reaction with 5 steps

1: acetic acid; bromine / 20 °C

2: sodium methylate / 1 h / 20 °C

3: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 1 h / 40 °C

4: dihydrogen peroxide; disodium tungstate dihydrate / methanol / 36 h / 0 - 20 °C

5: triethylamine / dichloromethane / 3 h / 0 - 20 °C

With disodium tungstate dihydrate; dihydrogen peroxide; bromine; sodium methylate; acetic acid; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; In methanol; dichloromethane; toluene;
DOI:10.1016/j.tetlet.2014.08.028

Reference yield:

: 70473-81-3
2,2,5,5-tetramethyl-2,5-dihydropyrrole-3-carboxylic acid methyl ester

: 76893-27-1
(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl methanesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 1 h / 40 °C

2: dihydrogen peroxide; disodium tungstate dihydrate / methanol / 36 h / 0 - 20 °C

3: triethylamine / dichloromethane / 3 h / 0 - 20 °C

With disodium tungstate dihydrate; dihydrogen peroxide; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; In methanol; dichloromethane; toluene;
DOI:10.1016/j.tetlet.2014.08.028