Beta-nicotinamide adenine dinucleotide phosphate tetrasodium salt (reduced form)

Base Information

• Chemical Name: Beta-nicotinamide adenine dinucleotide phosphate tetrasodium salt (reduced form)
• CAS No.: 2646-71-1
• Molecular Formula: C21H30 N7 O17 P3 . 4 Na
• Molecular Weight: 745.4209
• Hs Code.: 29349990
• European Community (EC) Number: 220-163-3
• Mol file: 2646-71-1.mol

Synonyms:2646-71-1;Nadph tetrasodium salt;NADPH (tetrasodium salt);C21H30N7O17P3.4Na;C21-H30-N7-O17-P3.4Na;Beta-triphosphopyridine nucleotide,sodium,reduced form;MFCD07366294;Beta-nicotinamide adenine dinucleotide phosphate tetrasodium salt (reduced form);beta-Nicotinamide adenine dinucleotide phosphate reduced tetrasodium salt hydrate

Chemical Property of Beta-nicotinamide adenine dinucleotide phosphate tetrasodium salt (reduced form)

Chemical Property:

• Melting Point: >250oC (dec.)
• Boiling Point: 1175.1 °C at 760 mmHg
• Flash Point: 664.5 °C
• PSA: 404.90000
• Density: 2.28 g/cmºC
• LogP: 0.40280
• Storage Temp.: −20°C
• Sensitive.: Light Sensitive
• Solubility.: 10 mM NaOH: soluble50mg/mL, clear
• Water Solubility.: Soluble in water (50 mg/ml).
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 26
• Rotatable Bond Count: 12
• Exact Mass: 905.0611392
• Heavy Atom Count: 56
• Complexity: 1380

Purity/Quality:

99%, ^*data from raw suppliers

b-Nicotinamide Adenine Dinucleotide Phosphate, reduced form, tetrasodium salt ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,F
• Statements: 36/37/38-11
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]
• Isomeric SMILES: C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]
• Description: NADPH is the reduced form of the coenzyme NADP+; used in anabolic reactions such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.NADPH, Tetrasodium Salt is a A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.
• Uses: One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2’position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydroge nases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. NADPH tetra sodium salt is used as an ubiquitous cofactor and biological reducing agent. β-NADPH is a coenzyme found in all living cells and is involved in redox reactions carrying electrons from one reaction to another. It is used as an electron donor, cofactor for many redox enzymes including nitric oxide synthetase. β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).