Technology Process of 9-Hexadecenoic acid, 16-hydroxy-, methyl ester, (9E)-
There total 1 articles about 9-Hexadecenoic acid, 16-hydroxy-, methyl ester, (9E)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl 9-decenoate; methyl non-8-enoate;
With
N-{[(1-{2-[(tert-butyldimethylsilyl)oxy]-3-(trifluoromethyl)-5,6,7,8-tetrahydronaphthalen-1-yl}-3-(trifluoromethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)oxy](2,5-dimethyl-1H-pyrrol-1-yl)(2-methyl-2-phenylpropylidene)molybdenumylidene}adamantan-1-amine;
In
benzene;
at 20 ℃;
for 6h;
Inert atmosphere;
Glovebox;
With
sodium methylate;
In
methanol;
at 20 ℃;
for 2h;
Overall yield = 68 %; Overall yield = 355 mg;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 91 percent / triethylamine / CH2Cl2 / 0.5 h / 0 °C
2: 90 percent / LAH / 1.) ether, 1h, reflux, 2.) rt
3: Br2, / CCl4
4: 74 percent / NaNH2, NH3 / tetrahydrofuran / 2 h
With
lithium aluminium tetrahydride; ammonia; bromine; sodium amide; triethylamine;
In
tetrahydrofuran; tetrachloromethane; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 91 percent / triethylamine / CH2Cl2 / 0.5 h / 0 °C
2: 90 percent / LAH / 1.) ether, 1h, reflux, 2.) rt
3: Br2, / CCl4
4: 74 percent / NaNH2, NH3 / tetrahydrofuran / 2 h
5: 97 percent / H2 / ethylendiamine poisoned P-2 Ni / ethanol
With
lithium aluminium tetrahydride; ammonia; hydrogen; bromine; sodium amide; triethylamine;
ethylendiamine poisoned P-2 Ni;
In
tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane;
