Prodelphinidin B6

Base Information

• Chemical Name: Prodelphinidin B6
• CAS No.: 61541-02-4
• Molecular Formula: C₂₁H₁₈O₉
• Molecular Weight: 414.369
• Mol file: 61541-02-4.mol

Synonyms:

Chemical Property of Prodelphinidin B6

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Prodelphinidin B6

There total 26 articles about Prodelphinidin B6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C49H42O9 (1242246-44-1) → (2R,3R,4S)-4-(2,4,6-trihydroxyphenyl)flavan-3,3',4',5,7-pentaol (61541-06-8,78284-51-2,79199-52-3,79199-53-4,104320-35-6,141605-03-0,61541-02-4)

Guidance literature:

With 20% palladium hydroxide on carbon; hydrogen; In tetrahydrofuran; methanol; water; at 20 ℃; for 4h; under 1500.15 Torr;

DOI:10.1016/j.bmc.2010.06.077

Reference yield: 80.0%

C49H42O9 (1242246-46-3) → catechin-(4α->2)-phloroglucinol (61541-02-4,78284-51-2,79199-52-3,79199-53-4,104320-35-6,141605-03-0,61541-06-8)

Guidance literature:

With 20% palladium hydroxide on carbon; hydrogen; In tetrahydrofuran; methanol; water; at 20 ℃; for 4h; under 1500.15 Torr;

DOI:10.1016/j.bmc.2010.06.077

Reference yield: 69.0%

5,7,3',4'-tetra-O-benzyl-4α-(1,3,5-tribenzylphloroglucinol)-catechin (157973-11-0) → catechin-(4α->2)-phloroglucinol (61541-02-4,78284-51-2,79199-52-3,79199-53-4,104320-35-6,141605-03-0,61541-06-8)

Guidance literature:

With hydrogen; palladium dihydroxide; In tetrahydrofuran; methanol; water;

DOI:10.1021/jo061740e

upstream raw materials:

3,5-dihydroxyphenol

epicatechin-(4β<*>6)-epicatechin-(4β<*>2)-phloroglucinol

phenylmethanethiol

epicatechin-(4β<*>8)-epicatechin-(4β<*>2)-phloroglucinol

Downstream raw materials:

cyanidin

Refernces

• 1、 Nakashima, Shohei,Oda, Chihiro,Masuda, Susumu,Tagashira, Motoyuki,Kanda, Tomomasa. "Isolation and structure elucidation of tetrameric procyanidins from unripe apples (Malus pumila cv. Fuji) by NMR spectroscopy". . p. 144 - 152. Retrieved 2012/11/13.
• 2、 Hayes, Christopher J.,Whittaker, Benjamin P.,Watson, Susan A.,Grabowska, Anna M.. "Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG)". . p. 9701 - 9712. Retrieved 2007/10/03.