2-Pentenoic acid, 4-methyl-, 1-methylethyl ester, (2E)-

Base Information

• Chemical Name: 2-Pentenoic acid, 4-methyl-, 1-methylethyl ester, (2E)-
• CAS No.: 80229-29-4
• Molecular Formula: C9H16O2
• Molecular Weight: 156.225
• Mol file: 80229-29-4.mol

Synonyms:

Chemical Property of 2-Pentenoic acid, 4-methyl-, 1-methylethyl ester, (2E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Pentenoic acid, 4-methyl-, 1-methylethyl ester, (2E)-

There total 1 articles about 2-Pentenoic acid, 4-methyl-, 1-methylethyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isobutyraldehyde (78-84-2) → 5,5-dimethyl-2,6-bis(propan-2-yl)-1,3-dioxan-4-ol (16889-18-2) + (Z)-isopropyl 4-methyl-2-pentenoate (87776-15-6) + 2-propyl 4-methyl-trans-2-pentenoate (80229-29-4)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; isopropyl (diphenylmethylsilyl)acetate; lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; Yield given. Yields of byproduct given;

Reference yield: 64.0%

phenyllithium (591-51-5) + 2-propyl 4-methyl-trans-2-pentenoate (80229-29-4) → (S)-4-methyl-3-phenylpentanoic acid isopropyl ester (256220-88-9)

Guidance literature:

phenyllithium; With Trimethyl borate; In diethyl ether; hexane; at -78 - -20 ℃; for 1.5h;

2-propyl 4-methyl-trans-2-pentenoate; With bis(ethylene)rhodium acetylacetonate; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); In 1,4-dioxane; diethyl ether; water; at 100 ℃; for 3h;

DOI:10.1016/S0957-4166(99)00417-6

Reference yield: 28.0%

phenyl trimethylsiloxane (2996-92-1,46143-12-8) + 2-propyl 4-methyl-trans-2-pentenoate (80229-29-4) → (S)-4-methyl-3-phenylpentanoic acid isopropyl ester (256220-88-9)

Guidance literature:

With (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; In 1,4-dioxane; water; at 90 ℃; for 20h;

DOI:10.1016/j.tetasy.2005.12.032

upstream raw materials:

isobutyraldehyde

Downstream raw materials:

(S)-4-methyl-3-phenylpentanoic acid isopropyl ester

(S)-(-)-3-phenyl-4-methylpentanoic acid

Refernces