1-Morpholin-4-yl-anthraquinone

Base Information

• Chemical Name: 1-Morpholin-4-yl-anthraquinone
• CAS No.: 7114-31-0
• Molecular Formula: C₁₈H₁₅NO₃
• Molecular Weight: 293.322
• NSC Number: 196449
• DSSTox Substance ID: DTXSID70307912
• Wikidata: Q82055515
• ChEMBL ID: CHEMBL1533229
• Mol file: 7114-31-0.mol

Synonyms:1-Morpholin-4-yl-anthraquinone;7114-31-0;1-morpholin-4-ylanthracene-9,10-dione;1-Morpholinoanthracene-9,10-dione;MLS000568291;SMR000175413;1-N-Morpholino-9,10-anthraquinone;NSC196449;1-morpholin-4-ylanthraquinone;cid_304457;CHEMBL1533229;SCHEMBL14983914;1-morpholino-9,10-anthraquinone;DTXSID70307912;BDBM114475;STK325063;1-morpholin-4-ylanthra-9,10-quinone;AKOS000520980;NSC-196449;1-(4-morpholinyl)anthracene-9,10-dione;1-(morpholin-4-yl)anthracene-9,10-dione;CS-0326571;FT-0608159;AG-690/40097109;1-(morpholin-4-yl)-9,10-dihydroanthracene-9,10-dione

Chemical Property of 1-Morpholin-4-yl-anthraquinone

Chemical Property:

• Vapor Pressure: 4.5E-11mmHg at 25°C
• Refractive Index: 1.643
• Boiling Point: 524 °C at 760 mmHg
• Flash Point: 270.7 °C
• PSA: 46.61000
• Density: 1.319 g/cm³
• LogP: 2.36360
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 293.10519334
• Heavy Atom Count: 22
• Complexity: 457

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1C2=CC=CC3=C2C(=O)C4=CC=CC=C4C3=O

Technology Process of 1-Morpholin-4-yl-anthraquinone

There total 4 articles about 1-Morpholin-4-yl-anthraquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

morpholine (110-91-8,99108-56-2) + 1-di(cyclohexylamino)phosphoryloxy-9,9-dichloro-10-anthrone (212612-78-7) → 1-morpholino-9,10-anthraquinone (7114-31-0)

Guidance literature:

Heating;

DOI:10.1007/BF02503487

Reference yield:

1-hydroxyanthraquinone (129-43-1) → 1-morpholino-9,10-anthraquinone (7114-31-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 67 percent / PCl₅ / benzene / 0.5 h / Heating

2: 90 percent / benzene / 4 h

3: 89 percent / Heating

With phosphorus pentachloride; In benzene; 1: Substitution / 2: Substitution / 3: Substitution;

DOI:10.1007/BF02503487

Reference yield:

1-dichlorophosphoryloxy-9,9-dichloro-10-anthrone (129973-11-1) → 1-morpholino-9,10-anthraquinone (7114-31-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / benzene / 4 h

2: 89 percent / Heating

In benzene; 1: Substitution / 2: Substitution;

DOI:10.1007/BF02503487

upstream raw materials:

morpholine

1-chloroanthracene-9,10-dione

1-di(cyclohexylamino)phosphoryloxy-9,9-dichloro-10-anthrone

1-hydroxyanthraquinone

Refernces