2,6-Pyridinophane

Base Information

• Chemical Name: 2,6-Pyridinophane
• CAS No.: 56446-41-4
• Molecular Formula: C14H14N2O4
• Molecular Weight: 274.27
• Mol file: 56446-41-4.mol

Synonyms:2,5,11,14-tetraoxa-19,20-diazatricyclo-(3.3.1.1)icosa-1(19),6,8,10(20),15,17-hexaene;2,6-pyridinophane

Chemical Property of 2,6-Pyridinophane

Chemical Property:

• Melting Point: 215 - 216 °C
• PSA: 62.70000
• LogP: 1.70560
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 274.09535693
• Heavy Atom Count: 20
• Complexity: 240

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1COC2=NC(=CC=C2)OCCOC3=CC=CC(=N3)O1

Technology Process of 2,6-Pyridinophane

There total 2 articles about 2,6-Pyridinophane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-Dibromopyridine (626-05-1) + ethylene glycol (107-21-1) → 2,5,7,10-tetraoxa-1,6(2,6)-dipyridina-cyclodecaphane (56446-41-4)

Guidance literature:

Multistep reaction; (i) NaH, bis-(2-ethoxy-ethyl) ether, (ii) /BRN= 108922/;

DOI:10.1021/jo00429a003

Reference yield:

→ 2,5,7,10-tetraoxa-1,6(2,6)-dipyridina-cyclodecaphane (56446-41-4)

Guidance literature:

2,6-Dibrompyridin 4b, Aethylenglykol 3a/NaH;

DOI:10.1021/ja00844a060

upstream raw materials:

2,6-Dibromopyridine

ethylene glycol