1-benzyl-4-ethoxybenzene

Base Information

• Chemical Name: 1-benzyl-4-ethoxybenzene
• CAS No.: 35672-52-7
• Molecular Formula: C15H16 O
• Molecular Weight: 212.291
• Mol file: 35672-52-7.mol

Synonyms:Phenetole,p-benzyl- (6CI,7CI); NSC 71634

Chemical Property of 1-benzyl-4-ethoxybenzene

Chemical Property:

• Vapor Pressure: 0.000686mmHg at 25°C
• Boiling Point: 318.1°Cat760mmHg
• Flash Point: 124.8°C
• Density: 1.014g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-benzyl-4-ethoxybenzene

There total 16 articles about 1-benzyl-4-ethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene (461432-23-5) → 2-chloro-4'-ethoxydiphenylmethane (1662702-90-0) + 1-benzyl-4-ethoxybenzene (35672-52-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 3h; Reagent/catalyst;

Reference yield: 90.0%

tris-(4-ethoxy-phenyl)-bismuthine (90591-48-3) + benzyl chloride (100-44-7) → 1-benzyl-4-ethoxybenzene (35672-52-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c3ra46672h

Reference yield: 89.0%

benzyl bromide (100-39-0) + tris-(4-ethoxy-phenyl)-bismuthine (90591-48-3) → 1-benzyl-4-ethoxybenzene (35672-52-7)

Guidance literature:

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl acetamide; at 90 ℃; for 1h; chemoselective reaction;

DOI:10.1039/c3ra40413g

upstream raw materials:

ethyl bromide

p-benzylphenol

4-ethoxybenzophenone

benzyl chloride

Downstream raw materials:

(3-bromo-4-ethoxyphenyl)(phenyl)methanone

Refernces

• 1、 Rao, Maddali L. N.,Dhanorkar, Ritesh J.. "Threefold and chemoselective couplings of triarylbismuths with benzylic chlorides and iodides using palladium catalysis". . p. 13134 - 13144. Retrieved 2014/04/03.
• 2、 Pai,Bajpai,Deshpande,Samant. "Friedel-Crafts benzylation of arenes using FeCI3 impregnated montmorillonite K10". . p. 2267 - 2273. Retrieved 2007/10/03.