Lauryl methacrylate

Base Information

• Chemical Name: Lauryl methacrylate
• CAS No.: 142-90-5
• Deprecated CAS: 170292-57-6,1274821-28-1,279231-66-2,1274821-28-1
• Molecular Formula: C16H30O2
• Molecular Weight: 254.413
• Hs Code.: 2916.14 DERIVATION
• European Community (EC) Number: 205-570-6
• NSC Number: 5188
• UNII: B6L83074BZ
• DSSTox Substance ID: DTXSID4027103
• Nikkaji Number: J78.373K
• Wikidata: Q3395664
• Metabolomics Workbench ID: 125287
• ChEMBL ID: CHEMBL1903701
• Mol file: 142-90-5.mol

Synonyms:DMA, methacrylate;dodecyl methacrylate;lauryl methacrylate

Chemical Property of Lauryl methacrylate

Chemical Property:

• Appearance/Colour: clear colorless to yellowish liquid
• Vapor Pressure: 0.000274mmHg at 25°C
• Melting Point: -7 °C(lit.)
• Refractive Index: 1.444 - 1.445
• Boiling Point: 322.7 °C at 760 mmHg
• Flash Point: 133.8 °C
• PSA: 26.30000
• Density: 0.874 g/cm³
• LogP: 5.02660
• Storage Temp.: 0-6°C
• Water Solubility.: insoluble
• XLogP3: 7.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 13
• Exact Mass: 254.224580195
• Heavy Atom Count: 18
• Complexity: 221

Purity/Quality:

99% ^*data from raw suppliers

Lauryl methacrylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, N
• Hazard Codes: Xi,N
• Statements: 36/37/38-50/53
• Safety Statements: 26-28-60-61-28B

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Plastics & Rubber -> (Meth)acrylates
• Canonical SMILES: CCCCCCCCCCCCOC(=O)C(=C)C
• Recent ClinicalTrials: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Salbutamol vs Long-acting Muscarinic Antagonists
• Uses: Miniemulsion polymerization of laurel methacrylate has been reported. Atom transfer radical polymerization and consecutive block copolymerization with methyl methacrylate has been investigated. Preparation of LMA based monolithic columns for CEC has been reported. LMA is used as a co-stabilizer to retard Ostwald ripening effect.

Technology Process of Lauryl methacrylate

There total 6 articles about Lauryl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) + 1-dodecyl alcohol (112-53-8) → n-dodecyl methacrylate (142-90-5)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1016/j.molliq.2017.04.040

Reference yield: 79.0%

1-dodecyl alcohol (112-53-8) + 3-(2-methylpropenoyl)-oxazolidin-2-one (31978-13-9) → n-dodecyl methacrylate (142-90-5)

Guidance literature:

With ytterbium(III) triflate; In acetonitrile; at 90 ℃; for 48h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.8b01896

Reference yield: 70.99%

1-dodecyl alcohol (112-53-8) + methacrylic acid methyl ester (80-62-6,114512-63-9,143476-91-9,25188-98-1,9011-14-7) → n-dodecyl methacrylate (142-90-5)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; dibutyltin dilaurate; zirconium(IV) acetylacetonate; Reagent/catalyst; Autoclave; Reflux; Large scale;

upstream raw materials:

1-dodecyl alcohol

methacrylic acid methyl ester

poly(methacrylic acid)

3-(2-methylpropenoyl)-oxazolidin-2-one

Downstream raw materials:

dodecyl isobutyrate

Refernces

• 1、 Fouilloux, Hugo,Placet, Vincent,Qiang, Wei,Robert, Carine,Thomas, Christophe M.. "Multicatalytic Transformation of (Meth)acrylic Acids: a One-Pot Approach to Biobased Poly(meth)acrylates". . p. 19374 - 19382. Retrieved 2021/07/21.
• 2、 -. "Preparation method of lauryl methacrylate". Paragraph 0029-0031. . Retrieved 2017/01/17.