2,3,5-TRIFLUOROBENZOTRIFLUORIDE

Base Information

• Chemical Name: 2,3,5-TRIFLUOROBENZOTRIFLUORIDE
• CAS No.: 392-91-6
• Molecular Formula: C₇H₂F₆
• Molecular Weight: 200.083
• Hs Code.: 2903999090
• Mol file: 392-91-6.mol

Synonyms:2,3,4,6-TETRA-O-BENZOYL-D-GALACTOPYRANOSE;2,3,5-Trifluorobenzotrifluoride;2,3,5-Trifluorbenzotrifluorid;1,2,5-Trifluor-3-trifluormethyl-benzol;1,2,5-trifluoro-3-trifluoromethyl-benzene;

Chemical Property of 2,3,5-TRIFLUOROBENZOTRIFLUORIDE

Chemical Property:

• Vapor Pressure: 32.2mmHg at 25°C
• Boiling Point: 107°Cat760mmHg
• Flash Point: 21.1°C
• PSA: 0.00000
• Density: 1.475g/cm³
• LogP: 3.12270

Purity/Quality:

98%min ^*data from raw suppliers

2,3,5-TRIFLUOROBENZOTRIFLUORIDE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5-TRIFLUOROBENZOTRIFLUORIDE

There total 6 articles about 2,3,5-TRIFLUOROBENZOTRIFLUORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

perfluorotoluene (434-64-0) → 1,2,5-trifluoro-3-(trifluoromethyl)benzene (392-91-6)

Guidance literature:

With tris[2-phenylpyridinato-C₂,N]iridium(III); N-ethyl-N,N-diisopropylamine; In acetonitrile; at 0 ℃; for 45h; Inert atmosphere; Irradiation;

DOI:10.1021/ja500031m

Reference yield:

perfluorotoluene (434-64-0) → 2,5-difluoro(trifluoromethyl)benzene (393-38-4) + 1,2,5-trifluoro-3-(trifluoromethyl)benzene (392-91-6)

Guidance literature:

Multi-step reaction with 2 steps

1: C₄₆H₅₁N₂P₂Rh; triethylsilane / benzene-d6 / 20 h / 90 °C / Schlenk technique; Glovebox; Inert atmosphere; Sealed tube

2: C₄₆H₅₁N₂P₂Rh; triethylsilane / benzene-d6 / 20 h / 90 °C / Schlenk technique; Glovebox; Inert atmosphere; Sealed tube

With triethylsilane; C₄₆H₅₁N₂P₂Rh; In benzene-d6;

DOI:10.1021/om500827d

Reference yield:

1,2,3,4-tetrafluoro-5-(trifluoromethyl)benzene (654-53-5) → 1,2,5-trifluoro-3-(trifluoromethyl)benzene (392-91-6)

Guidance literature:

With triethylsilane; C₄₄H₄₇N₂P₂Rh; In benzene-d6; at 90 ℃; for 20h; Catalytic behavior; Schlenk technique; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1021/om500827d

upstream raw materials:

perfluorotoluene

1,2,3,4-tetrafluoro-5-(trifluoromethyl)benzene

Downstream raw materials:

2,3,5-trifluorobenzoic acid

Refernces

• 1、 Jaeger, Alma D.,Walter, Ruben,Ehm, Christian,Lentz, Dieter. "Gallium Hydrides and O/N-Donors as Tunable Systems in C?F Bond Activation". supporting information. p. 2908 - 2915. Retrieved 2018/09/20.