N,N,N',N'-Tetraethylphthalamide

Base Information Edit

Chemical Name:N,N,N',N'-Tetraethylphthalamide
CAS No.:83-81-8
Molecular Formula:C16H24 N2 O2
Molecular Weight:276.379
Hs Code.:2924299090
European Community (EC) Number:201-504-5
NSC Number:16071
UNII:22TJ09HM80
DSSTox Substance ID:DTXSID6058899
Nikkaji Number:J192.611J
Wikidata:Q27253666
Mol file:83-81-8.mol

Synonyms:Neospiran;Analetil;Geastigmol;Geastimol;83-81-8;o-Phthalic acid bis(diethylamide);Cardiovital;Unispiran;neo-Cardiamine;Phthalethamide;N,N,N',N'-Tetraethylphthalamide;Coretonin;1,2-Benzenedicarboxamide, N,N,N',N'-tetraethyl-;Tetraethylbis(phthalamide);TETRAETHYLPHTHALAMIDE;o-Phthalylbis(diethylamide);EINECS 201-504-5;NSC 16071;Phthalamide, N,N,N',N'-tetraethyl-;BRN 2506823;Bis-diethylamid kyseliny ftalove [Czech];UNII-22TJ09HM80;AI3-20596;Bis-diethylamid kyseliny ftalove;orthophthalic acid didiethylamide;N,N,N',N'-Tetraethyl-1,2-benzenedicarboxamide;22TJ09HM80;1,2-Benzenedicarboxamide, N1,N1,N2,N2-tetraethyl-;NSC-16071;N,N,N',N'-tetraethylbenzene-1,2-dicarboxamide;4-09-00-03266 (Beilstein Handbook Reference);o-Phthalic acid bis[diethylamide];1-N,1-N,2-N,2-N-tetraethylbenzene-1,2-dicarboxamide;Tetraethylbisphthalamide;o-Phthalyl-bis-diethylamide;SCHEMBL610480;N,N',N'-Tetraethylphthalamide;1, N,N,N',N'-tetraethyl-;DTXSID6058899;N,N,N',N'-Tetraaethylphthalamid;CHEBI:135143;Phthalamide,N,N',N'-tetraethyl-;NSC16071;N1,N1,N2,N2-tetraethylphthalamide;STK493679;AKOS003239261;LS-109088;FT-0631384;N~1~,N~1~,N~2~,N~2~-tetraethylphthalamide;Q27253666

Suppliers and Price of N,N,N',N'-Tetraethylphthalamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TETRAETHYLBISPHTHALAMIDE 98.00%
10G
$ 1674.75

Total 9 raw suppliers

Chemical Property of N,N,N',N'-Tetraethylphthalamide Edit

Chemical Property:

Melting Point:39°
Refractive Index:1.5800 (estimate)
Boiling Point:bp 175-180°
Flash Point:196.9oC
PSA：40.62000
Density:1.0209 (rough estimate)
LogP:2.65060
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:276.183778013
Heavy Atom Count:20
Complexity:290

Purity/Quality:

98%min ^*data from raw suppliers

TETRAETHYLBISPHTHALAMIDE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1=CC=CC=C1C(=O)N(CC)CC

Technology Process of N,N,N',N'-Tetraethylphthalamide

There total 9 articles about N,N,N',N'-Tetraethylphthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 88-95-9
Phthaloyl dichloride

: 996-50-9
N,N-diethyl-1,1,1-trimethylsilanamine

: 83-81-8
N,N-diethyl 2-(N,N-diethylcarboxamido)benzamide

Guidance literature:: In hexane; Ambient temperature;
DOI:10.1021/jo00170a050

Reference yield: 56.0%

: 109-89-7
diethylamine

: 88-99-3,73607-73-5
benzene-1,2-dicarboxylic acid

: 83-81-8
N,N-diethyl 2-(N,N-diethylcarboxamido)benzamide

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; benzenesulfonyl chloride; In acetone; at 20 - 23 ℃; for 0.0833333h;

Reference yield:

: 4166-52-3
2-(diethylcarbamoyl)benzoic acid

: 83-81-8
N,N-diethyl 2-(N,N-diethylcarboxamido)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / SOCl₂ / CHCl₃ / 2 h / Heating

2: H₂, quinoline, S / 10percent Pd/BaSO₄ / xylene / Heating

With quinoline; thionyl chloride; hydrogen; Pd-BaSO₄; In chloroform; xylene;
DOI:10.1002/ardp.19813140804