5-azoniaspiro[4.4]nonane

Base Information

• Chemical Name: 5-azoniaspiro[4.4]nonane
• CAS No.: 16450-38-7
• Molecular Formula: C8H16 N . Br
• Molecular Weight: 206.126
• European Community (EC) Number: 835-166-0
• DSSTox Substance ID: DTXSID80466504
• NSC Number: 28372
• Mol file: 16450-38-7.mol

Synonyms:5-Azoniaspiro[4.4]nonane,bromide (6CI,7CI,8CI,9CI); 1,1'-Spirobipyrrolidinium bromide

Chemical Property of 5-azoniaspiro[4.4]nonane

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 205.04661
• Heavy Atom Count: 10
• Complexity: 79.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC[N+]2(C1)CCCC2.[Br-]

Technology Process of 5-azoniaspiro[4.4]nonane

There total 6 articles about 5-azoniaspiro[4.4]nonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

pyrrolidine (123-75-1) + 1,4-dibromo-butane (110-52-1) → 5-azoniaspiro<4.4>nonane bromide (16450-38-7)

Guidance literature:

With resin Amberlite A₂₆; In acetonitrile; for 6h; Solvent; Temperature; Time; Reflux;

Reference yield: 78.35%

1,4-dibromo-butane (110-52-1) → 5-azoniaspiro<4.4>nonane bromide (16450-38-7)

Guidance literature:

With ammonium hydroxide; In 2-methyltetrahydrofuran; at 30 ℃; for 9h;

Reference yield:

1-(4-bromo-butyl)-pyrrolidine → 5-azoniaspiro<4.4>nonane bromide (16450-38-7)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/jo01353a004

upstream raw materials:

pyrrolidine

1,4-dibromo-butane

Downstream raw materials:

pyrrolidine

5-azonia-spiro[4.4]nonane picrate

5-azonia-spiro[4.4]nonane bis(diphenylphosphinomethyl)diphenylborate

(C₄H₈)2N⁽¹⁺⁾*(C₆H₅)2PC₆H₄B(C₆H₅)3^(1-)=((C₄H₈)2N)((C₆H₅)2PC₆H₄B(C₆H₅)3)

Refernces

• 1、 -. "Method For Preparing spiro quarternary ammonium salt". Paragraph 0106; 0107; 0124; 0128; 0132; 0136. . Retrieved 2018/05/03.
• 2、 Li, Hao,Li, Shichao,Zhang, Ye,Yan, Feng. "Inorganic salt templated porous TiO2 photoelectrode for solid-state dye-sensitized solar cells". . p. 346 - 352. Retrieved 2016/01/09.