Dodecanoic acid, 4-chlorophenyl ester

Base Information

• Chemical Name: Dodecanoic acid, 4-chlorophenyl ester
• CAS No.: 83491-06-9
• Molecular Formula: C18H27ClO2
• Molecular Weight: 310.864
• Mol file: 83491-06-9.mol

Synonyms:

Chemical Property of Dodecanoic acid, 4-chlorophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dodecanoic acid, 4-chlorophenyl ester

There total 3 articles about Dodecanoic acid, 4-chlorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-dodecanoyl chloride (112-16-3) + 4-chloro-phenol (106-48-9,82344-39-6) → 4-chlorophenyl dodecanoate (83491-06-9)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1021/jo00294a009

Reference yield:

4-(4'-chlorophenoxy)benzonitrile (74448-92-3) + dodecanethioic acid S-p-tolyl ester (102020-26-8) → (4-cyanophenyl)(4-methylphenyl)sulfide (104128-50-9) + 4-chlorophenyl dodecanoate (83491-06-9)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); o-phenylenebis(diphenylphosphine); In chlorobenzene; for 5h; Inert atmosphere; Reflux;

DOI:10.1021/acs.joc.6b02585

Reference yield:

lauric acid (143-07-7) + 4-chloro-phenol (106-48-9,82344-39-6) → 4-chlorophenyl dodecanoate (83491-06-9)

Guidance literature:

With sulfuric acid; xylene; Entfernen des entstehenden Wassers;

upstream raw materials:

lauric acid

4-chloro-phenol

n-dodecanoyl chloride

4-(4'-chlorophenoxy)benzonitrile

Downstream raw materials:

lauric acid

4-chloro-phenol

4-chlorophenolate

laurate anion

Refernces

• 1、 Al-Awadi, Nouria,Williams, Andrew. "Effective Charge Development in Ester Hydrolysis Catalyzed by Cationic Micelles". . p. 2001 - 2004. Retrieved 2007/10/02.