Technology Process of 2-Propanol, 1-(octadecyloxy)-3-(phenylmethoxy)-, (S)-
There total 11 articles about 2-Propanol, 1-(octadecyloxy)-3-(phenylmethoxy)-, (S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-octadecanol;
With
sodium hydride;
In
tetrahydrofuran; oil;
at 0 - 80 ℃;
(S)-benzyl glycidyl ether;
In
tetrahydrofuran; N,N-dimethyl-formamide; oil;
at 20 - 80 ℃;
With
water;
In
tetrahydrofuran; N,N-dimethyl-formamide; oil;
at 20 ℃;
for 0.333333h;
DOI:10.1021/ja901412j
- Guidance literature:
-
With
diisobutylaluminium hydride;
at 0 ℃;
for 0.333333h;
DOI:10.1248/cpb.32.791
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2 / 5percent Pd/C / tetrahydrofuran / Ambient temperature
2: phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature
3: 66 percent / LiAlH4 / tetrahydrofuran / Ambient temperature
4: 71 percent / pyridine / CH2Cl2 / 48 h / Ambient temperature
5: toluene / 1 h / 80 °C
With
pyridine; lithium aluminium tetrahydride; hydrogen; triethylamine; trichlorophosphate;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; chloroform; toluene;
DOI:10.1002/hlca.19820650339